Bacteriophage Taxonomy: A Continually Evolving Discipline.

Bacteriophage Taxonomy: A Continually Evolving Discipline.
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噬菌体分类学:一门不断发展的学科。

DOI:
10.1007/978-1-0716-3523-0_3
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发表时间:
2024
期刊:
Methods in molecular biology (Clifton, N.J.)
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通讯作者:
Turner D
Turner D
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文献类型:
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作者:
Turner D

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虽然分类学是一个经常被低估的科学分支,但它发挥着非常重要的作用。噬菌体分类学已经从一门主要基于形态学(以 David Bradley 和 Hans-Wolfgang Ackermann 的工作为特征)的学科发展到今天采用的基于序列的方法。国际病毒分类委员会 (ICTV) 的细菌病毒小组委员会在决定新病毒的分类位置之前,通过测量整体 DNA 和蛋白质相似性以及系统发育,采用整体方法对原核生物病毒进行分类。美国国家生物技术信息中心(NCBI)和其他公共数据库存放的大量完整基因组导致对许多病毒的分类学进行重新评估,未来将看到新的病毒家族和更高阶病毒的引入。
While taxonomy is an often underappreciated branch of science, it serves very important roles. Bacteriophage taxonomy has evolved from a discipline based mainly on morphology, characterized by the work of David Bradley and Hans-Wolfgang Ackermann, to the sequence-based approach that is taken today. The Bacterial Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) takes a holistic approach to classifying prokaryote viruses by measuring overall DNA and protein similarity and phylogeny before making decisions about the taxonomic position of a new virus. The huge number of complete genomes being deposited with the National Center for Biotechnology Information (NCBI) and other public databases has resulted in a reassessment of the taxonomy of many viruses, and the future will see the introduction of new viral families and higher orders.