Inhibition of ubiquitin ligase F-box andWD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krueppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice
Inhibition of ubiquitin ligase F-box andWD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krueppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice
复制标题
抑制泛素连接酶 F-box 和含有 7α (Fbw7α) 的 WD 重复结构域会通过 Krueppel 样因子 5 (KLF5)/过氧化物酶体增殖物激活受体 γ2 (PPARγ2) 途径引起小鼠肝脂肪变性，但不会引起小鼠的 SREBP-1c 蛋白
作者：
Kumadaki S;Karasawa T;Matsuzaka T;Ema M;Nakagawa Y;Nakakuki M;Saito R;Yahagi N;Iwasaki H;Sone H;Takekoshi K;Yatoh S;Kobayashi K;Takahashi A;Suzuki H;Takahashi S;Yamada N;Shimano H
