Prevalence of Primary Open Angle Glaucoma in a Rural Adult Chinese Population: The Handan Eye Study
Prevalence of Primary Open Angle Glaucoma in a Rural Adult Chinese Population: The Handan Eye Study
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DOI：
10.1167/iovs.11-7472
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发表时间：
2011-10-01
影响因子：
4.4
通讯作者：
Wang, Ning Li
中科院分区：
文献类型：
--
作者：
Liang, Yuan Bo;Friedman, David S.;Wang, Ning Li
目的.评估中国北方农村人群原发性开角型青光眼（POAG）的患病率及其相关性。在中国邯郸的一个农村县，随机选择了13个村庄的6716名成年人参加了这项研究。所有参与者都完成了全面的眼科检查，包括眼内压（IOP），裂隙灯检查和眼底评估。对青光眼患者进行视野检查。65人（1.2%）患有POAG，40岁及以上人群的校正患病率为1.0%（95%置信区间[CI]，0.7% - 1.3%）。性别与POAG无显著相关性（P > 0.05）。年龄（比值比[OR]，1.9; 95% CI，1.4-2.5，每增加10年），IOP（OR，1.5;每增加5 mm Hg，95% CI 1.2-2.0），轴长多因素分析显示，中度近视（3.1 -6.0 D; OR，4.7; 95% CI，1.6-13.5）增加POAG的风险。POAG患者的平均IOP为16.3 +/- 3.5 mm Hg，其中90%的患者出现IOP
PURPOSE. To estimate the prevalence and associations of primary open angle glaucoma (POAG) in a rural population of northern China.METHODS. In a rural county in Handan, China, 6716 adults residing in 13 villages were randomly selected and participated in the study. All participants completed a comprehensive eye examination, including intraocular pressure (IOP), slit-lamp examination, and fundus evaluation. Visual fields were obtained with on glaucoma suspects.RESULTS. Sixty-five persons (1.2%) had POAG, with an adjusted prevalence of 1.0% (95% confidence interval [CI], 0.7% - 1.3%) in those aged 40 years and older. Sex was not significantly associated with POAG (P > 0.05). Age (odds ratio [OR], 1.9; 95% CI, 1.4-2.5, for each 10-year increase), IOP (OR, 1.5; 95% CI 1.2-2.0 for each 5-mm Hg increase), axial length (OR, 1.3; 95% CI, 1.1-1.6), and moderate myopia (3.1-6.0 D; OR, 4.7; 95% CI, 1.6-13.5) increased the risk for POAG in multivariate analysis. The mean IOP of persons with POAG was 16.3 +/- 3.5 mm Hg, and 90% of them presented with an IOP