A model for mechanical structure of the alveolar duct.
A model for mechanical structure of the alveolar duct.
复制标题
肺泡管机械结构模型。
DOI：
10.1152/jappl.1982.52.4.1064
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Bachofen,H
中科院分区：
文献类型：
--
作者：
Wilson,TA;Bachofen,H
灌注固定的空气和盐水填充的肺的透射和扫描电子显微镜照片中显示的肺的微观结构的外观表明肺泡管的结构的以下模型。有两个受力元件网络。第一个是外周结缔组织系统的相互依赖的部分，从胸膜开始并延伸到叶间和小叶间裂。在小叶下水平，其几何形状尚不完全清楚。该网络通过肺体积的变化而扩展，并且对表面张力不敏感。第二网络由形成齿槽开口的边缘的线元件组成。这个网络是围绕支气管、细支气管和动脉的轴向纤维系统的末端部分。这个网络的线元素通过表面张力的向外力而延伸。形成肺泡的二维肺泡壁是可忽略的机械部件，除了作为空气-液体界面处的表面张力的平台。该模型的力学分析产生的表面积，反冲压力，肺容量，和表面张力之间的关系，是一致的肺容量低于80%的总肺容量的已发表的数据。
The appearance of the microstructure of the lung as revealed in transmission and scanning electron micrographs of perfusion-fixed air- and saline-filled lungs suggests the following model for the structure of the alveolar duct. There are two networks of force-bearing elements. The first is an interdependent part of the peripheral connective tissue system that starts from the pleura and extends into the interlobar and interlobular fissures. At the sublobular level, its geometry is not yet fully clear. This network is extended by changes in lung volume and is insensitive to surface tension. The second network is composed of the line elements that form the rims of the alveolar openings. This network is the terminal part of the axial fiber system that surrounds bronchi, bronchioli, and arteries. The line elements of this network are extended by the outward force of surface tension. The two-dimensional alveolar walls that form the alveoli are negligible mechanical components except as platforms for surface tension at the air-liquid interface. An analysis of the mechanics of this model yields relations among surface area, recoil pressure, lung volume, and surface tension that are consistent with published data for lung volumes below 80% of total lung capacity.