The representation of the human oral area in the somatosensory cortex: a functional MRI study
The representation of the human oral area in the somatosensory cortex: a functional MRI study
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DOI：
10.1093/cercor/bhj012
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发表时间：
2006-05-01
期刊：
影响因子：
3.7
通讯作者：
Sadato, N
中科院分区：
文献类型：
--
作者：
Miyamoto, JJ;Honda, M;Sadato, N
牙齿的触觉参与各种口腔功能，如咀嚼和说话。使用功能性磁共振成像，我们研究了口腔区域的皮质感觉表征，包括牙齿。首先，我们确定了嘴唇、牙齿和舌头在中央后回（GpoC）中的体位表征。触觉刺激应用于下唇、舌头和牙齿。每个刺激激活的病灶用激活区的重心（COG）来表征。其次，我们根据每个感觉表征之间的重叠，检查了GPoC中躯体组织的东侧-尾侧变化。在GPoC的吻侧部分，牙齿表征的COG位置明显高于舌头，低于嘴唇，与Penfield提出的经典“感觉小丘”一致；然而，这种体位表征在GPoC的中部和尾部部分变得不清楚。GPoC的中部和尾部部分的重叠程度明显大于GPoC的吻侧部分。这些发现支持了一种理论，即来自口腔结构的输入在初级体感皮层上分层聚集。
The tactile sensation of the teeth is involved in various oral functions, such as mastication and speech. Using functional magnetic resonance imaging, we investigated the cortical sensory representation of the oral area, including the teeth. First, we identified the somatotopic representation of the lips, teeth and tongue in the postcentral gyrus (GpoC). Tactile stimuli were applied to the lower lip, tongue and teeth. The foci activated by each stimulus were characterized by the center of gravity (COG) of activated areas. Secondly, we examined the rostro-caudal changes in the somatotopic organization in the GPoC in terms of the overlap between each sensory representation. In the rostral portion of the GPoC, the COG of the representation of teeth was located significantly superior to that of the tongue and inferior to that of the lip, consistent with the classical 'sensory homunculus' proposed by Penfield; however, this somatotopic representation became unclear in the middle and caudal portions of the GPoC. The overlap between each representation in the middle and caudal portions of the GPoC was significantly greater than that in the rostral portion of the GPoC. These findings support the theory that the input from oral structures converges hierarchically across the primary somatosensory cortex.