Risk factors for glaucoma filtering bleb infections
Risk factors for glaucoma filtering bleb infections
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DOI：
10.1001/archopht.118.3.338
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发表时间：
2000-03-01
影响因子：
--
通讯作者：
Ritch, R
中科院分区：
文献类型：
--
作者：
Soltau, JB;Rothman, RF;Ritch, R
目的：探讨青光眼滤过术后滤过泡相关性眼部感染的危险因素。研究方法：进行了一项病例对照研究，比较了1990年1月1日至1998年6月30日期间所有连续的青光眼滤过泡相关感染病例（55例患者的55只眼）与匹配的对照眼。当在滤过泡内发现粘液脓性浸润并伴有轻度至中度眼前节炎症时，滤过泡相关感染被归类为滤过泡炎。患眼内炎的眼睛有前房积脓、前玻璃体腔内细胞或玻璃体活检取样结果阳性。根据手术医生、青光眼手术日期和类型以及所用抗纤维化药物的类型，为每例病例选择对照。使用年龄、种族、性别、诊断、既往切口手术次数、滤过泡位置和滤过泡渗漏的存在进行多变量、匹配、病例对照logistic回归分析，以确定哪些变量与滤过泡相关感染相关。结果如下：在术后任何时间，与滤过泡相关的感染眼并发迟发性滤过泡漏的几率是未感染眼发生迟发性滤过泡漏几率的25.8倍（P
Objective: To determine risk factors for bleb-related ocular infection after glaucoma filtering surgery. Methods: A case-control study comparing all consecutive cases of glaucoma filtering bleb-related infections (55 eyes of 55 patients) with matched control eyes between January 1, 1990, and June 30, 1998, was performed. Bleb-related infection was classified as blebitis when a mucopurulent infiltrate was identified within the bleb and associated Kith mild to moderate anterior segment inflammation. Eyes with endophthalmitis had hypopyon, cells in the anterior vitreous cavity, or a positive vitreous biopsy sampling result. A control was selected for each case based on matching of the surgeon, date and type of glaucoma surgery, and type of antifibrotic agent used. Multivariate, matched, case-control logistic regression analysis was performed using age, race, sex, diagnosis, number of previous incisional operations, filtering bleb location, and presence of bleb leak to determine which variables were associated with bleb-related infection. Results: The odds of an eye with a bleb-related infection being seen with a concomitant late-onset bleb leak are 25.8 times the odds of a noninfected eye having a late-onset bleb leak at any time in the postoperative period (P