ENDOMETRIAL THICKNESS APPEARS TO BE A SIGNIFICANT FACTOR IN EMBRYO IMPLANTATION IN IN-VITRO FERTILIZATION

ENDOMETRIAL THICKNESS APPEARS TO BE A SIGNIFICANT FACTOR IN EMBRYO IMPLANTATION IN IN-VITRO FERTILIZATION
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DOI:
10.1093/oxfordjournals.humrep.a136061
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发表时间:
1995-04-01
期刊:
影响因子:
6.1
通讯作者:
ROSENWAKS, Z
ROSENWAKS, Z
中科院分区:
医学1区
文献类型:
--
作者:
NOYES, N;LIU, HC;ROSENWAKS, Z

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为了评价子宫内膜厚度和类型在体外受精(IVF)中的作用,我们前瞻性地测量了516个IVF胚胎移植周期的这些参数。妊娠率和胚胎种植率分别评估每毫米子宫内膜厚度和三种子宫内膜类型。子宫内膜厚度>9 mm的患者的胚胎植入率、临床妊娠率和持续妊娠率(分别为24.4%、48.6%和42.2%)显著高于子宫内膜厚度>9 mm的患者,环形和中间型子宫内膜模式表明IVF妊娠预后更好,但子宫内膜较薄和表现出固体构型的患者的妊娠结局可接受。
To evaluate the role of endometrial thickness and pattern in in-vitro fertilization (IVF), these parameters were prospectively measured in 516 cycles of IVF with embryo transfer at our clinic. Pregnancy and embryo implantation rates were assessed for each mm of endometrial thickness and for each of three endometrial patterns. Embryo implantation, clinical and ongoing pregnancy rates were significantly higher in the patients with an endometrial thickness >9 mm (24.4, 48.6 and 42.2% respectively) compared with those of 9 mm as well as ring and intermediate endometrial patterns denoted a more favourable prognosis for pregnancy in IVF but thinner endometrium and those exhibiting a solid configuration had an acceptable pregnancy outcome.