MORTALITY AND HALLUCINATIONS IN NURSING-HOME PATIENTS WITH ADVANCED PARKINSONS-DISEASE
MORTALITY AND HALLUCINATIONS IN NURSING-HOME PATIENTS WITH ADVANCED PARKINSONS-DISEASE
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DOI：
10.1212/wnl.45.4.669
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发表时间：
1995-04-01
期刊：
影响因子：
9.9
通讯作者：
STEBBINS, GT
中科院分区：
文献类型：
--
作者：
GOETZ, CG;STEBBINS, GT
我们对进入疗养院的 11 名晚期帕金森病 (PD) 患者进行了 5 年的监测，并评估了疗养院护理的长期性、死亡率和幻觉状态。最初的研究结束两年后，这些患者都没有从疗养院出院，并且全部死亡。疗养院患者的死亡率显着高于 22 名年龄、性别和病程匹配的社区 PD 患者。幻觉状态总体稳定； 82% 的患者在两次评估中具有相同的幻觉状态（存在或不存在）。来自原社区对照组的四名受试者在随访期间进入疗养院。尽管这些患者与社区中其余 18 名患者的运动和智力障碍评分相似，但转移到疗养院的患者中出现幻觉的情况明显更多。该研究证明了晚期 PD 疗养院安置的永久性以及与此类安置相关的高死亡率。它还记录了这些晚期帕金森病患者幻觉行为的长期性，并强化了我们之前报道的关于幻觉与长期护理机构安置之间关系的观察结果。
We monitored 11 patients with advanced Parkinson's disease (PD) who entered nursing homes over a 5-year period and assessed chronicity of nursing home care, mortality, and hallucinatory status. Two years after the original study's close, none of these patients had ever been discharged from the nursing homes and all were dead. The mortality rate among the nursing home patients was significantly greater than that in 22 community-dwelling subjects with PD who were matched for age, gender, and disease duration. Hallucinatory status was generally stable; 82% of patients had the same hallucinatory status (presence or absence) at the two assessments. Four subjects from the original community-dwelling control group entered nursing homes during the follow-up period. Whereas motor and intellectual impairment scores were similar between these patients and the remaining 18 in the community, the presence of hallucinations was significantly greater among patients transferred to nursing homes. The study demonstrates the permanency of nursing home placement in advanced PD and the high mortality associated with such placement. It also documents the chronicity of hallucinatory behavior in these patients with advanced PD and reinforces our previously reported observations on the relationship between hallucinations and placement in chronic-care facilities.