Cationic and neutral ruthenium(II) complexes containing both arene or Cp* and functionalized aminophosphines. Application to hydrogenation of aromatic ketones
Cationic and neutral ruthenium(II) complexes containing both arene or Cp* and functionalized aminophosphines. Application to hydrogenation of aromatic ketones
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DOI：
10.1016/j.jorganchem.2010.07.030
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发表时间：
2010-11-01
影响因子：
2.3
通讯作者：
Baysal, Akin
中科院分区：
文献类型：
--
作者：
Aydemir, Murat;Baysal, Akin
氢转移还原过程由于其操作简单而引起合成化学家越来越多的兴趣。为此，以[Ru（eta 6-p-cymene）（mu-Cl）Cl] 2或[RuCp*Cl（COD）]为原料，合成了一系列新型的钌（II）与P-N-P配体的配合物。配合物的分析和光谱方法进行了充分的表征。（31）P-{（1）H} NMR、DEPT、（1）H-（13）C HETCOR或（1）H-（1）H COSY相关实验用于确认光谱归属。配合物5、6和7在异PrOH作为氢源存在下催化苯乙酮衍生物转移氢化为1-苯基乙醇衍生物。催化研究表明，所有的配合物是良好的催化前体的苯乙酮衍生物在0.1 M的异-PrOH溶液中的转移氢化。值得注意的是，5作为优异的催化剂，以高达99%（TOF）的优异转化率得到相应的醇
Hydrogen transfer reduction processes are attracting increasing interest from synthetic chemists in view of their operational simplicity. For this aim, a series of novel Ru(II) complexes with the P-N-P ligands were synthesized starting from the complex [Ru(eta 6-p-cymene)(mu-Cl) Cl] 2 or [RuCp*Cl(COD)]. The complexes were fully characterized by analytical and spectroscopic methods. (31)P-{(1)H} NMR, DEPT, (1)H-(13)C HETCOR or (1)H-(1)H COSY correlation experiments were used to confirm the spectral assignments. Complexes 5, 6 and 7 catalyze the transfer hydrogenation of acetophenone derivatives to 1-phenylethanol derivatives in the presence of iso-PrOH as the hydrogen source. Catalytic studies showed that all complexes are excellent catalytic precursors for the transfer hydrogenation of acetophenone derivatives in 0.1 M iso-PrOH solution. Notably 5 acts as an excellent catalyst giving the corresponding alcohols in excellent conversions up to 99% (TOF