Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography
Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography
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DOI：
10.1148/radiology.214.2.r00fe18363
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发表时间：
2000-02-01
期刊：
影响因子：
19.7
通讯作者：
Hittmair, K
中科院分区：
文献类型：
--
作者：
Fleischmann, D;Rubin, GD;Hittmair, K
目的：比较计算机断层（CT）血管造影中单期注射造影剂与个体化双期注射造影剂获得的主动脉髂混浊均匀性。材料与方法：32例腹主动脉瘤患者行CT血管造影。在16例患者（第一组）中，以4 mL/秒的流速给予120 mi的造影剂。在其他16例患者（第二组）中，通过对每位患者对标准化测试注射的时间衰减响应进行数学反卷积来计算双相注射方案。衰减均匀性量化为增强值的“平台偏差”，其计算方法为30秒扫描周期内观测到的时间连续衰减值-：的SD值。结果：组2患者接受77 ~ 165 mt（平均115 mL）造影剂。最初4-6秒的初始流速范围为4.1至10.0 mL/秒（平均6.8 mL/秒）；在剩余的24-26秒内，持续流速范围为2.0至4.8 mL/秒（平均3.1 mL/秒）。2组患者的平台偏差（19 HU）明显大于1组患者（38 HU, P < 0.001）。结论：在CT血管造影中，与标准单期注射造影剂相比，量身定制的双期注射可使主动脉髂壁增强更均匀。
PURPOSE: To compare the uniformity of aortoiliac opacification obtained from uniphasic contrast medium injections versus individualized biphasic injections at computed tomographic (CT) angiography.MATERIALS AND METHODS: Thirty-two patients with an abdominal aortic aneurysm underwent CT angiography. In 16 patients (group 1), 120 mi of contrast material was administered at a flow rate of 4 mL/sec. In the other 16 patients (group 2) biphasic injection protocols were computed by using mathematic deconvolution of each patient's time-attenuation response to a standardized test injection. Attenuation uniformity was quantified as the "plateau deviation" of enhancement values, which were calculated as the SD of the time-contiguous attenuation values -:observed during the 30-second scanning period.RESULTS: Group 2 patients received between 77 and 165 mt (mean, 115 mL) of contrast medium. Initial flow rates ranged from 4.1 to 10.0 mL/sec (mean, 6.8 mL/sec) for the first 4-6 seconds; continuing flow rates ranged from 2.0 to 4.8 mL/sec, (mean, 3.1 mL/sec) for the remaining 24-26 seconds. The plateau deviation was significantly mailer in group 2 patients (19 HU) versus group 1 patients (38 HU, P < .001).CONCLUSION: At CT angiography, tailored biphasic injections led to more uniform aortoiliac enhancement, compared with standard uniphasic injections of contrast medium.