Excretion of β-Aminoisobutyric Acid by Man
Excretion of β-Aminoisobutyric Acid by Man
复制标题
人体对 β-氨基异丁酸的排泄
DOI：
10.1016/s0021-9258(18)81204-2
复制
发表时间：
1963
影响因子：
4.8
通讯作者：
T. Kappe
中科院分区：
文献类型：
--
作者：
M. D. Armstrong;K. Yates;Y. Kakimoto;K. Taniguchi;T. Kappe
9例受试者在24 h内经尿液排泄11 - 150 mg β-氨基异丁酸。一些东方人一直排泄大量的粪便，这似乎是一种遗传特征。当3名受试者口服天然酸异构体时，尿液中的回收率范围为55%至102%。天然的D-（-）异构体是胸腺嘧啶催化剂的中间体，它比L-（+）异构体更不容易被破坏，并且涉及不同的酶系统。A.赫普本。
Nine subjects excreted 11 to 150 mg β-amino-isobutyric acid in urine in 24 h. Some Orientals consistently excreted large amounts and that appeared to be a genetic trait. When the natural acid isomer was given by mouth to 3 subjects recoveries in urine ranged from 55 to 102%. The natural D-(-) isomer which is an intermediate of thymine catabolism was destroyed less readily than the L-(+) isomer and different enzyme systems were involved. A. Hepburn.