SYNTHESIS AND CHARACTERIZATION OF NEUTRAL HYDROGEN ION-SELECTIVE CHROMOIONOPHORES FOR USE IN BULK OPTODES
SYNTHESIS AND CHARACTERIZATION OF NEUTRAL HYDROGEN ION-SELECTIVE CHROMOIONOPHORES FOR USE IN BULK OPTODES
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DOI：
10.1016/0003-2670(93)85102-p
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发表时间：
1993-06-22
影响因子：
6.2
通讯作者：
SIMON, W
中科院分区：
文献类型：
--
作者：
BAKKER, E;LERCHI, M;SIMON, W
所讨论的离子选择性传感器的类型是基于具有光学转换（本体光电二极管）的溶剂聚合物膜，并且需要分析物离子可逆地质量转移到有机相的本体中和从有机相的本体中转移。除了要分析的离子之外，这种传感器还同时测量参考离子。出于分析目的，吸收可见光范围内的光的H+选择性载体（色离子载体）与离子选择性电极已知的离子载体一起掺入膜中。一系列中性H+-选择性的色离子载体，合成，以期他们可能使用散装光电极，进行了描述。在不同的溶剂中的碱性，亲油性，化学稳定性，选择性，摩尔吸光系数和最大吸收的各种研究的结果给出，并在理论上进行了部分讨论。结果表明，所描述的色离子载体是高度选择性的，并提供了广泛的碱性。它们的亲脂性通常保证在水溶液和稀释的血液和血清中的应用的长寿命，但对于未稀释的血液样品中的测量，它们应该共价固定到光电极膜的聚合物上。它们的化学稳定性通常是足够的，只有阳光直射才会引起快速分解。
The type of ion-selective sensors discussed is based on a solvent polymeric membrane with optical transduction (bulk optode), and requires a reversible mass transfer of analyte ions into and from the bulk of the organic phase. Apart from the ion to be analysed, such sensors simultaneously measure a reference ion. For analytical purposes, an H+-selective carrier absorbing light in the visible range (chromoionophore) is incorporated in the membrane together with an ionophore as known from ion-selective electrodes. A series of neutral H+-selective chromoionophores, synthesized with a view to their possible use in bulk optodes, are described. The results of various studies on the basicity in different solvents, lipophilicity, chemical stability, selectivity, molar absorption coefficients and absorbance maxima are given and, in part, discussed theoretically. It is shown that the chromoionophores described are highly selective and offer a wide range of basicities. Their lipophilicity usually guarantees a long lifetime for applications in both aqueous solutions and diluted blood and serum, but for measurements in undiluted blood samples they should be covalently immobilized to the polymer of the optode membrane. Their chemical stability is usually sufficient, only direct sunlight causing rapid decomposition.