Wallenberg's lateral medullary syndrome: Clinical-magnetic resonance imaging correlations

Wallenberg's lateral medullary syndrome: Clinical-magnetic resonance imaging correlations
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瓦伦堡延髓外侧综合征:临床与磁共振成像的相关性

DOI:
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发表时间:
1993
期刊:
影响因子:
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通讯作者:
J. Mohr
J. Mohr
中科院分区:
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文献类型:
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作者:
R. Sacco;L. Freddo;J. Bello;J. Odel;S. Onesti;J. Mohr

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·目标。- 将延髓外侧梗死患者的临床和影像学表现相关联。设计- 具有脑成像的“盲法”评价的病例系列。设置. - 纽约神经学研究所(NY)的住院和门诊患者。患者1983年至1989年间,卒中中心对33例连续的延髓外侧综合征患者进行了评估。结果- 共济失调(70%)、同侧面部或对侧身体麻木(64%)、眩晕(51%)和吞咽困难(51%)是发病时最常见的症状。11例患者有眼部症状(复视或视力模糊)。霍纳综合征的发生率为91%,同侧共济失调的发生率为85%,对侧痛觉减退的发生率为85%。眼球震颤(61%)和面部无力(42%)较少见。头部计算机断层扫描是异常的,只有当小脑梗死存在(3例)。在22例病例中获得的磁共振成像,其中2例正常; 12例仅存在延髓外侧梗死,8例发现病变延伸到延髓外侧。面部无力或眼部症状与超出外侧髓区的梗死之间没有相关性。73%的患者通过血管成像或超声检查证实椎动脉疾病。结论. - 霍纳综合征、同侧共济失调和对侧痛觉减退三联征将在临床上识别出外侧延髓梗死患者。面部无力和眼部症状是常见的,并不一定意味着梗死延伸到延髓外侧。小脑梗死很少伴有延髓外侧综合征,这表明尽管椎动脉闭塞的发生率很高,但小脑后下动脉的大部分区域是保留的。
• Objective. —To correlate clinical and radiologic findings in patients with lateral medullary infarction. Design. —Case series with "blinded" evaluation of brain imaging. Setting. —Hospitalized and ambulatory patients at the Neurological Institute of New York (NY). Patients. —Thirty-three consecutive patients with lateral medullary syndrome were evaluated by the Stroke Center between 1983 and 1989. Results. —Ataxia (70%), numbness either of the ipsilateral face or of the contralateral body (64%), vertigo (51 %), and dysphagia (51%) were the most frequent symptoms at onset. Eleven patients had ocular symptoms (diplopia or blurred vision). Horner's syndrome was found in 91 %, ipsilateral ataxia in 85%, and contralateral hypalgesia in 85%. Nystagmus (61%) and facial weakness (42%) were less frequent. Head computed tomography was abnormal only when a cerebellar infarction was present (three cases). Magnetic resonance imaging, obtained in 22 cases, was normal in two; a lateral medullary infarction alone was present in 12, and a lesion extending beyond the lateral medulla was found in eight. No correlation was noted between facial weakness or ocular symptoms and infarction extending beyond the lateral medullary region. Vertebral artery disease was confirmed by vascular imaging or insonation studies in 73% of patients. Conclusions. —The triad of Horner's syndrome, ipsilateral ataxia, and contralateral hypalgesia will clinically identify patients with lateral medullary infarction. Facial weakness and ocular symptoms are frequent and do not necessarily imply that the infarction extends beyond the lateral medulla. Cerebellar infarcts only infrequently accompany lateral medullary syndrome, suggesting that most of the posterior inferior cerebellar artery territory is spared, despite the high frequency of vertebral artery occlusion.
DOI: 10.1161/01.str.15.3.417
发表时间: 1984
期刊: Stroke
影响因子: 8.3
作者:
Kistler,JP;Buonanno,FS;DeWitt,LD;Davis,KR;Brady,TJ;Fisher,CM
通讯作者: Fisher,CM