A clinical trial of a slow-releasing fluoride device in children
A clinical trial of a slow-releasing fluoride device in children
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DOI：
10.1159/000084798
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发表时间：
2005-01-01
期刊：
影响因子：
4.2
通讯作者：
Curzon, MEJ
中科院分区：
文献类型：
--
作者：
Toumba, KJ;Curzon, MEJ
目的是测试含氟缓释装置预防儿童龋齿的效果。因此，聚集了居住在英国利兹高龋齿率、低社会经济地区的 174 名 8 岁儿童。两种缓释/溶解玻璃（SFG）颗粒，一种含有氟化物（F），一种不含氟化物，被随机附着在儿童的上颌磨牙上。使用标准指数记录基线龋齿如 dmft/s、DMFT/S、牙周病、菌斑和牙石。餐后 2 小时收集未刺激的唾液样本用于 F 分析。所有参数在 2 年内每隔 6 个月进行一次测量。共有 132 名儿童完成了试验，其中 63 名儿童（测试 n = 31，对照 n = 32）最终仍保留着玻璃装置。牙龈健康和牙结石平均值的比较显示，在整个试验过程中，各组之间没有差异。试验结束时的平均龋齿 DMFS (2.26) 显着低于对照组儿童 (SFG, 2.26) (8.41; p
The objective was to test a fluoride-containing slow-release device in preventing dental caries in children. Accordingly a population of 174 children aged 8 years living in a high-caries, low socio-economic area of Leeds (UK) was assembled. Two slow-release/dissolving glass (SFG) pellets, one with fluoride (F) and one without, were randomly attached to the maxillary molars of the children. Baseline caries as dmft/s, DMFT/S, periodontal disease, plaque and calculus were recorded using standard indices. Unstimulated saliva samples were collected 2 h postprandial for F analysis. All parameters were measured at 6-month intervals for 2 years. There were 132 children completing the trial of whom 63 (test n = 31, control n = 32) still retained the glass devices at the end. Comparison of mean values for gingival health and calculus showed no differences between groups throughout the trial. Mean caries as dmfs at the end of the trial (2.26) was significantly lower for the test (SFG, 2.26) compared with that for the control children (8.41; p