CHANGES IN TRANSCRIPTION IN HL-60 CELLS FOLLOWING EXPOSURE TO ALTERNATING CURRENTS FROM ELECTRIC-FIELDS
CHANGES IN TRANSCRIPTION IN HL-60 CELLS FOLLOWING EXPOSURE TO ALTERNATING CURRENTS FROM ELECTRIC-FIELDS
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DOI：
10.1016/0302-4598(92)80021-8
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发表时间：
1992-08-01
期刊：
影响因子：
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通讯作者：
GOODMAN, R
中科院分区：
文献类型：
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作者：
BLANK, M;SOO, L;GOODMAN, R
本文报道了不同场强和暴露时间对暴露于60 Hz电场（正弦波）的HL-60细胞中组蛋白H2 B和c-myc转录水平的影响。观察到这些正常表达的转录本的基础水平增加，这取决于场强和暴露时间。β-2-微球蛋白，一种已知不可诱导的转录物，不受细胞暴露于这些实验中使用的场强的影响。
The effect of varying field strength and exposure time on histone H2B and c-myc transcript levels in HL-60 cells exposed to 60 Hz electric fields (sine waves) is reported here. An increase in the basal levels of these normally expressed transcripts was observed, which was dependent on both field strength and time of exposure. Beta-2-microglobulin, a transcript known to be uninducible, was unaffected by cellular exposure to the field strengths used in these experiments.