Functional magnetic resonance imaging of human visual cortex during face matching: A comparison with positron emission tomography
Functional magnetic resonance imaging of human visual cortex during face matching: A comparison with positron emission tomography
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DOI：
10.1006/nimg.1996.0025
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发表时间：
1996-08-01
期刊：
影响因子：
5.7
通讯作者：
Haxby, JV
中科院分区：
文献类型：
--
作者：
Clark, VP;Keil, K;Haxby, JV
仅使用功能磁共振成像(FMRI)识别与面孔感知相关的皮质区域。使用改良的1.5T GE Signa MRI获得T2*加权梯度回波、平面回波图像。在所有9名研究对象中，面孔匹配任务的完成与枕颞叶腹侧皮质MR信号显著增强的区域有关，该区域从枕下沟延伸到枕颞沟外侧和梭形回。在枕顶背侧皮质靠近顶内沟的区域，信号增加的幅度较小，变化较大。角回和扣带回后部信号减弱。单一受试者的fMRI分析显示，激活的离散区域有明确的边界。对空间平滑的fMRI数据进行分组分析，得出的结果复制了之前使用正电子发射断层扫描(PET)进行的面部处理研究的大部分方面。这些结果表明，正电子发射计算机断层扫描和功能磁共振成像识别具有相似解剖位置的功能区。此外，功能磁共振成像以更高的解剖精度揭示了更高水平加工区的解剖位置的个体间差异。(C)1996年Acdaemal Press，Inc.
Cortical areas associated with the perception of faces mere identified using functional magnetic resonance imaging (fMRI). T2*-weighted gradient echo, echo-planar MR images were obtained using a modified 1.5-T GE Signa MRI. In all nine subjects studied, performance of a face-matching task was associated with a region of significantly increased MR signal in the ventral occipitotemporal cortex, extending from the inferior occipital sulcus to the lateral occipitotemporal sulcus and fusiform gyrus. Smaller and more variable signal increases were found in dorsolateral occipitoparietal cortex near the intraparietal sulcus. Signal decreases were found in the angular gyrus and posterior cingulate cortex. Single-subject fMRI analyses revealed discrete areas of activation with well-defined borders. Group analyses of spatially smoothed fMRI data produced results that replicated most aspects of previous studies of face processing using positron emission tomography (PET). These results show that PET and fMRI identify functional areas with similar anatomical locations. In addition, fMRI reveals interindividual variation in the anatomical location of higher-level processing areas with greater anatomical precision. (C) 1996 Acdaemic Press, Inc.