[Assessment of congenital heart disease by a thallium-201 SPECT study in children: accuracy of estimated right to left ventricular pressure ratio].
[Assessment of congenital heart disease by a thallium-201 SPECT study in children: accuracy of estimated right to left ventricular pressure ratio].
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[通过铊201 SPECT 研究评估儿童先天性心脏病：估计右心室与左心室压力比的准确性]。
DOI：
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发表时间：
1993
影响因子：
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通讯作者：
T. Ohno
中科院分区：
文献类型：
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作者：
I. Ishii;K. Nakajima;J. Taki;M. Taniguchi;H. Bunko;N. Tonami;K. Hisada;T. Ohno
探讨各种先天性心脏病患儿右左心室收缩压比（RVp/LVp）与铊-201右左心室计数比（201Tl R/L）的相关性特征。采用配备平行孔或扇形光束准直器的高分辨率三头SPECT系统。在102例患者中，RVp/LVp与201Tl R/L平均计数比在平面（R = 0.89, p = 0.0001）和SPECT （R = 0.80, p = 0.0001）均具有良好的相关性。SPECT定量分析心肌摄取显示了每种疾病的特征模式以及右心室负荷过重类型的差异。对各心脏病进行线性回归分析时，室间隔缺损相关性最强。复杂心脏异常也与RVp/LVp呈正相关（r = 0.51, p = 0.05），可用于估计右心室压力。法洛四联症合并肺动脉狭窄手术治疗后，201Tl R/L计数比的降低与右室负荷的改善一致。我们认为，201Tl SPECT研究可以作为估计右心室压力的一个很好的指标。
The characteristics of correlation between the right-to-left ventricular systolic pressure ratios (RVp/LVp) and the thallium-201 right-to-left ventricular (201Tl R/L) count ratios was investigated in children with various congenital heart diseases. High-resolution three-headed SPECT system equipped with either parallel-hole or fan-beam collimators was used. In a total of 102 patients, the correlation between RVp/LVp and 201Tl R/L average count ratios was good in both planar (r = 0.89, p = 0.0001) and SPECT studies (r = 0.80, p = 0.0001). Quantitative analysis of myocardial uptake by SPECT demonstrated the characteristic pattern of each disease as well as the differences in the right ventricular overload types. When the linear regression analysis was performed in each heart disease, ventricular septal defect showed most excellent correlation. Complex heart anomalies also showed positive correlation (r = 0.51, p = 0.05) with RVp/LVp, and it can be used to estimate right ventricular pressure. After surgical treatment of tetralogy of Fallot and pulmonary stenosis, the decrease of 201Tl R/L count ratio was in accordance with improvement of right ventricular overload. We conclude that 201Tl SPECT study can be a good indicator for estimation of right ventricular pressure.