ILLUSORY MOVEMENTS PRODUCED BY ELECTRICAL-STIMULATION OF LOW-THRESHOLD MUSCLE AFFERENTS FROM THE HAND
ILLUSORY MOVEMENTS PRODUCED BY ELECTRICAL-STIMULATION OF LOW-THRESHOLD MUSCLE AFFERENTS FROM THE HAND
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DOI：
10.1093/brain/108.4.965
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发表时间：
1985-12-01
期刊：
影响因子：
14.5
通讯作者：
GANDEVIA, SC
中科院分区：
文献类型：
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作者：
GANDEVIA, SC
关于肌肉传入在运动感觉中的作用，一直存在争议。Moberg(1983)最近声称，以前使用的许多证据支持肌肉传入的动觉作用，指出皮肤传入(远离关节但覆盖相关肌肉)的关键作用，并且没有确定的证据表明‘肌腱’受体对动觉的贡献。在本研究中，通过表面探头、针电极或运动束内的微电极(通过表面探头、针电极或微电极)传递到腕部尺神经的一连串电刺激会产生手指的虚幻运动和位置扭曲。这些错觉发生在没有明显的运动(刺激是运动阈值的0.5-0.9倍)和没有皮肤感觉异常的情况下。平滑幻觉运动的速度随刺激频率的增加而增加。幻觉运动的方向与手部固有肌肉缩短所产生的方向相反。在错觉过程中，从对侧头皮记录到短潜伏期的脑电位。这些错觉最简单的解释是感觉到低阈值肌肉传入的放电，可能是那些支配初级肌梭末梢的传入。刺激指神经有时会产生指间关节极端位置的感觉或关节的明显摆动。振荡频率随刺激频率的增加而增加。这些结果支持初级肌梭传入对运动感觉的直接贡献，尽管它们不排除非肌肉传入的贡献。
There is continuing controversy as to the role of muscle afferents in kinaesthesia. Moberg (1983) has recently claimed that much of the evidence previously used in favour of a kinaesthetic role for muscle afferents points to a crucial role for cutaneous afferents (remote from the joint but overlying the relevant muscle) and that there is no definite evidence for a contribution to kinaesthesia from ‘musculotendinous’ receptors. In the present study, trains of electrical stimuli delivered to the ulnar nerve at the wrist (through a surface probe, needle electrode or microelectrode within motor fascicles) produced illusory movements of the fingers and distortions in their position. These illusions occurred in the absence of overt movement (stimuli were 0.5–0.9 times motor threshold) and in the absence of cutaneous paraesthesiae. The velocity of the smooth illusory movements increased with the frequency of stimulation. The direction of the illusory movements was opposite to that produced by shortening of intrinsic muscles of the hand. Short-latency cerebral potentials were recorded from the contralateral scalp during the illusions. These illusions are most simply explained by the perception of discharges in low-threshould muscle afferents, probably those which innervate primary muscle spindle endings. Stimulation of the digital nerves sometimes produced a sensation of extreme position of one of the interphalangeal joints or of an apparent oscillation at the joint. The frequency of oscillation increased as the stimulus frequency increased. These results argue for a direct contribution to kinaesthesia from primary muscle spindle afferents though they do not exclude contributions from nonmuscle afferents.