Establishment of Streptococcus mutans in infants induces decrease in the proportion of salivaryα-haemolytic bacteria
Establishment of Streptococcus mutans in infants induces decrease in the proportion of salivaryα-haemolytic bacteria
复制标题
婴儿体内变形链球菌的建立导致唾液α-溶血菌比例下降
DOI：
10.1111/j.1365-263x.2011.01183.x
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发表时间：
2012
影响因子：
3.8
通讯作者：
Taku Fujiwara
中科院分区：
文献类型：
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作者：
Mamoru Kawaguchi;* Tomonori Hosohino;Takashi Ooshima;Taku Fujiwara
International Journal of Paediatric Dentistry 2012; 22：139 - 145 C.对于儿科牙医来说，评估婴儿龋齿风险的指标非常重要。传统上，变形链球菌的数量和/或比例被用作风险指标;然而，由于这些数字反映了现有情况，因此它们不适合评估尚未感染变形链球菌的婴儿的龋齿风险。因此，我们寻找了一个指标的建立ofS. mutans.方法。为了评估的变化所造成的建立ofS. mutans在婴儿口腔的微生物群，我们监测了变化的口腔微生物群的两个pre-dentate婴儿超过3年的时间，并在一项横断面研究的40名幼儿园学龄儿童的唾液培养非选择性血琼脂，缓解唾液琼脂，结果：两个纵向观察结果表明，变形链球菌的建立将诱导口腔微生物群中α-溶血性细菌的减少。这一建议得到了横断面研究结果的补偿，并且揭示了唾液中103 CFU/mL的变形链球菌的建立可以通过包含小于约55%的微生物群来预测。结论：发现婴儿唾液中α-溶血性细菌比例的降低可作为预测变形链球菌建立和评估龋齿的指标风险作为背景规划的牙齿护理和治疗的婴儿感染变形链球菌。
International Journal of Paediatric Dentistry 2012; 22: 139–145Objective.For paediatric dentists, an indicator to assess caries risk of infants is very important. Conventionally, the number and/or proportions ofStreptococcus mutanshave been employed as risk indicator; however, because such figures reflect the existing situation, they are not suitable for assessing caries risk of infants that have not yet been infected withS. mutans. Thus, we searched for an indicator for the establishment ofS. mutans.Methods.To evaluate the changes caused by the establishment ofS. mutansin the microbiota of the infant oral cavity, we monitored changes in the oral microbiota of two pre‐dentate infants over a 3‐year period and in a cross‐sectional study of 40 nursery school‐aged children by cultivation of saliva on nonselective blood agar, Mitis‐Salivarius agar, and Mitis‐Salivarius agar supplemented with bacitracin combined with identification of selected isolates.Results.Two longitudinal observations suggested that the establishment ofS. mutanswould induce a decrease in α‐haemolytic bacteria in the microbial population of the oral cavity. This suggestion was compensated with the results of cross‐sectional study, and it was revealed that the establishment of 103CFU/mL of mutans streptococci in saliva might be predicted by a microbiota comprising less than approximately 55% of α‐haemolytic.Conclusion.Decrease in the proportion of α‐haemolytic bacteria in saliva of infant was found to be applicable as an indicator to predict the establishment ofS. mutansand to assess dental caries risk as a background for planning of dental care and treatment in the infants before infection withS. mutans.