Unimolecular Submersible Nanomachines. Synthesis, Actuation, and Monitoring.
Unimolecular Submersible Nanomachines. Synthesis, Actuation, and Monitoring.
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DOI：
10.1021/acs.nanolett.5b03764
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发表时间：
2015-12-09
期刊：
影响因子：
10.8
通讯作者：
Tour JM
中科院分区：
文献类型：
--
作者：
García-López V;Chiang PT;Chen F;Ruan G;Martí AA;Kolomeisky AB;Wang G;Tour JM
合成了带有光驱动马达和荧光团的单分子潜水纳米机器。核磁共振实验表明，电机的旋转不会被荧光团淬灭，并且电机的行为方式与没有附加荧光团的相应电机相同。没有观察到光分解或热分解。通过仔细设计无电机和有慢电机的控制分子，我们发现单分子荧光相关光谱发现，当电机被紫外光完全激活时，只有转速快（MHz范围）的分子的扩散增强了26%。这表明USN分子在每次运动驱动时给出约9 nm的步长。非单向旋转电机也会导致较小的扩散，增加10%。本研究对溶液中电动分子的光致动有了新的认识。
Unimolecular submersible nanomachines (USNs) bearing light-driven motors and fluorophores are synthesized. NMR experiments demonstrate that the rotation of the motor is not quenched by the fluorophore and that the motor behaves in the same manner as the corresponding motor without attached fluorophores. No photo or thermal decomposition is observed. Through careful design of control molecules with no motor and with a slow motor, we found using single molecule fluorescence correlation spectroscopy that only the molecules with fast rotating speed (MHz range) show an enhancement in diffusion by 26% when the motor is fully activated by UV light. This suggests that the USN molecules give ∼9 nm steps upon each motor actuation. A non-unidirectional rotating motor also results in a smaller, 10%, increase in diffusion. This study gives new insight into the light actuation of motorized molecules in solution.