FRACTIONAL MOVING BLOOD-VOLUME - ESTIMATION WITH POWER DOPPLER US

FRACTIONAL MOVING BLOOD-VOLUME - ESTIMATION WITH POWER DOPPLER US
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DOI:
10.1148/radiology.197.1.7568820
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发表时间:
1995-10-01
期刊:
影响因子:
19.7
通讯作者:
CARSON, PL
CARSON, PL
中科院分区:
医学1区
文献类型:
--
作者:
RUBIN, JM;ADLER, RS;CARSON, PL

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目得:为了估计与功率多普勒超声(US)的组织中的移动的血液的分数。材料和方法:功率多普勒超声测量的移动散射体在流管作为一个功能的连续稀释的灌注液。将测量值相对于最高浓度下流管中心的最大多普勒功率进行归一化,并用于计算每次运行的灌注液稀释分数,每次稀释用于代表样本体积中非移动软组织的增加量。该技术也被应用到两个临床exam.RESULTS:连续稀释的灌注液中的流动experiment表现出单调的,线性下降的多普勒功率作为dilution.CONCLUSION的函数:功率多普勒US技术有可能更准确地估计血流的变化,并具有作为一个连续的参数,可以深度归一化的优势。
PURPOSE: To estimate the fraction of moving blood in tissue with power Doppler ultrasound (US).MATERIALS AND METHODS: Power Doppler US measurements of moving scatterers in a flow tube were made as a function of successive dilutions of the perfusate. Measurements were normalized relative to the maximum Doppler power in the center of the flow tube at the highest concentration and were used to calculate the fractional dilution of the perfusate for each run with each dilution used to represent increasing amounts of nonmoving soft tissue in the sample volume. The technique was also applied to two clinical examples.RESULTS: Successive dilutions of the perfusate in the flow experiment showed a monotonic, linear decrease in the Doppler power as a function of dilution.CONCLUSION: The power Doppler US technique has the potential to more accurately estimate alterations in blood flow and has the advantage of being a continuous parameter that can be depth normalized.