Reporting Standards for Chronic Pancreatitis by Using CT, MRI, and MR Cholangiopancreatography: The Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer
Reporting Standards for Chronic Pancreatitis by Using CT, MRI, and MR Cholangiopancreatography: The Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer
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DOI：
10.1148/radiol.2018181353
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发表时间：
2019-01-01
期刊：
影响因子：
19.7
通讯作者：
Dasyam, Anil K.
中科院分区：
文献类型：
--
作者：
Tirkes, Temel;Shah, Zarine K.;Dasyam, Anil K.
慢性胰腺炎是胰腺的一种炎症性疾病，临床表现包括腹痛、急性胰腺炎、外分泌和/或内分泌功能障碍以及胰腺癌。有必要对表型良好的患者进行纵向研究，以确定慢性胰腺炎的横断面成像结果在诊断和评估疾病严重程度方面的效用。CT和MR胆管造影是评估慢性胰腺炎最常用的横断成像研究。目前，慢性胰腺炎没有统一的报告标准。慢性胰腺炎的几个特征应用于临床，如钙化，实质T1信号改变，局灶性或弥漫性腺体萎缩，或腺体轮廓不规则。这些发现尚未纳入标准化的诊断标准。对于慢性胰腺炎疾病严重程度的量化也缺乏共识，除了单独使用剑桥分类中描述的导管特征。慢性胰腺炎、糖尿病和胰腺癌研究联盟（CPDPC）由美国国家糖尿病、消化和肾脏疾病研究所与美国国家癌症研究所于2015年成立，开展慢性胰腺炎、糖尿病和胰腺腺癌的合作研究。来自成人慢性胰腺炎工作组的CPDPC研究者的任务是开发一种新的共识方法来报告慢性胰腺炎的特征，旨在标准化临床试验中疾病严重程度的诊断和评估。本共识声明提出并定义了慢性胰腺炎的特征以及推荐的报告指标。(c) RSNA， 2018年
Chronic pancreatitis is an inflammatory condition of the pancreas with clinical manifestations ranging from abdominal pain, acute pancreatitis, exocrine and/or endocrine dysfunction, and pancreatic cancer. There is a need for longitudinal studies in well-phenotyped patients to ascertain the utility of cross-sectional imaging findings of chronic pancreatitis for diagnosis and assessment of disease severity. CT and MR cholangiopancreatography are the most common cross-sectional imaging studies performed for the evaluation of chronic pancreatitis. Currently, there are no universal reporting standards for chronic pancreatitis. Several features of chronic pancreatitis are applied clinically, such as calcifications, parenchymal T1 signal changes, focal or diffuse gland atrophy, or irregular contour of the gland. Such findings have not been incorporated into standardized diagnostic criteria. There is also lack of consensus on quantification of disease severity in chronic pancreatitis, other than by using ductal features alone as described in the Cambridge classification. The Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC) was established by the National Institute of Diabetes and Digestive and Kidney Diseases and the National Cancer Institute in 2015 to undertake collaborative studies on chronic pancreatitis, diabetes mellitus, and pancreatic adenocarcinoma. CPDPC investigators from the Adult Chronic Pancreatitis Working Group were tasked with development of a new consensus approach to reporting features of chronic pancreatitis aimed to standardize diagnosis and assessment of disease severity for clinical trials. This consensus statement presents and defines features of chronic pancreatitis along with recommended reporting metrics. (c) RSNA, 2018