NUT midline carcinoma in the right orbit: a case report
NUT midline carcinoma in the right orbit: a case report
复制标题
DOI：
10.1080/15384047.2019.1598761
复制
发表时间：
2019-04-18
影响因子：
3.6
通讯作者：
Du, Yuqing
中科院分区：
文献类型：
--
作者：
Ding, Tingting;Wang, Yajin;Du, Yuqing
摘要睾丸中线癌是一种罕见的恶性肿瘤，其发生于染色体15q14上的NUT基因易位。这种非常罕见的肿瘤通常位于中线结构，特别是在头部和颈部。然而，以前没有关于眼睛引起的NMC的报道。在这里，我们首先描述了一个案件的NMC起源于右眼眶的一个60岁的女人。在临床实践中采用了包括手术、化疗、放疗和靶向治疗的多模式方法。
Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare malignant tumor defined by a unique chromosomal translocation of the NUT gene on chromosome 15q14. This very rare tumor is usually located in midline structures, especially in the head and neck region. However, there have been no previous reports of NMC arising from the eyes. Here, we first describe a case of NMC originating in the right orbit of a 60-year-old woman. A multimodality approach, including surgery, chemotherapy, radiotherapy, and target therapy, was adopted in clinical practice.