Adipose triglyceride lipase (Atgl) mediates the antibiotic jinggangmycin-stimulated reproduction in the brown planthopper, Nilaparvata lugens Stål.
Adipose triglyceride lipase (Atgl) mediates the antibiotic jinggangmycin-stimulated reproduction in the brown planthopper, Nilaparvata lugens Stål.
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DOI：
10.1038/srep18984
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发表时间：
2016-01-07
影响因子：
4.6
通讯作者：
Wu JC
中科院分区：
文献类型：
--
作者：
Jiang YP;Li L;Liu ZY;You LL;Wu Y;Xu B;Ge LQ;Song QS;Wu JC
抗生素井冈霉素（JGM）是国内广泛应用于防治水稻纹枯病的农药产品。出乎意料的是，它刺激了褐飞虱（BPH）， Nilaparvata lugens （statl）的繁殖。然而，刺激的潜在分子机制尚不清楚。目前的研究表明，脂肪甘油三酯脂肪酶（Atgl）是参与jgm刺激BPH繁殖的酶之一。在JGM处理的雌性（JGM + dsAtgl）中，Atgl的沉默消除了JGM刺激的BPH雌性的繁殖力。此外，敲低Atgl显著降低了JGM + dsAtgl雌性卵巢和脂肪体中繁殖所需的蛋白质和甘油含量。我们认为Atgl是jgm诱导BPH繁殖的关键酶之一。
The antibiotic jinggangmycin (JGM) is an agrochemical product widely used in China for controlling rice sheath blight, Rhizoctonia solani. Unexpectedly, it stimulates reproduction in the brown planthopper (BPH), Nilaparvata lugens (Stål). However, the underlying molecular mechanisms of the stimulation are unclear. The present investigation demonstrates that adipose triglyceride lipase (Atgl) is one of the enzymes involved in the JGM-stimulated reproduction in BPH. Silence of Atgl in JGM-treated (JGM + dsAtgl) females eliminated JGM-stimulated fecundity of BPH females. In addition, Atgl knockdown significantly reduced the protein and glycerin contents in the ovaries and fat bodies of JGM + dsAtgl females required for reproduction. We conclude that Atgl is one of the key enzymes responsible for JGM-stimulated reproduction in BPH.