Differential Processing of Consonance and Dissonance within the Human Superior Temporal Gyrus.
Differential Processing of Consonance and Dissonance within the Human Superior Temporal Gyrus.
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DOI：
10.3389/fnhum.2016.00154
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发表时间：
2016
影响因子：
2.9
通讯作者：
Knight RT
中科院分区：
文献类型：
--
作者：
Foo F;King-Stephens D;Weber P;Laxer K;Parvizi J;Knight RT
众所周知，听觉皮层对音乐感知至关重要，包括对和谐和不和谐的感知。关于和谐和不和谐感知的神经相关性的研究主要采用了人类的非侵入性电生理和功能成像技术以及动物的神经生理记录，但人类听觉皮层内的细粒度时空动力学仍然未知。我们记录了皮质电图（ECoG）信号直接从外侧表面的左或右颞叶的8例患者接受神经外科治疗，因为他们被动地听高度和谐和高度不和谐的音乐和弦。我们评估了上级颞回（STG）内高γ（γ高，70-150 Hz）频率范围内的ECoG活动，并观察了两种类型的大脑半球皮层感兴趣的部位：一种类型的γ高活动在协和和弦和不协和和弦之间没有显著差异，另一种类型的γ高反应在刺激开始后75 - 200 ms之间增加。此外，这些部位的一个子集对不同类型的不和谐和弦表现出额外的敏感性，并且在两个半球中观察到γ高功率变化与刺激粗糙度之间的正相关性。我们还观察到一个独特的空间组织的皮质网站在正确的STG，不和谐的敏感网站位于前面的非敏感网站。总之，这些研究结果表明，差异处理的和谐和不和谐的双边STG与右半球表现出强大的和空间组织的敏感性不和谐。
The auditory cortex is well-known to be critical for music perception, including the perception of consonance and dissonance. Studies on the neural correlates of consonance and dissonance perception have largely employed non-invasive electrophysiological and functional imaging techniques in humans as well as neurophysiological recordings in animals, but the fine-grained spatiotemporal dynamics within the human auditory cortex remain unknown. We recorded electrocorticographic (ECoG) signals directly from the lateral surface of either the left or right temporal lobe of eight patients undergoing neurosurgical treatment as they passively listened to highly consonant and highly dissonant musical chords. We assessed ECoG activity in the high gamma (γhigh, 70–150 Hz) frequency range within the superior temporal gyrus (STG) and observed two types of cortical sites of interest in both hemispheres: one type showed no significant difference in γhigh activity between consonant and dissonant chords, and another type showed increased γhigh responses to dissonant chords between 75 and 200 ms post-stimulus onset. Furthermore, a subset of these sites exhibited additional sensitivity towards different types of dissonant chords, and a positive correlation between changes in γhigh power and the degree of stimulus roughness was observed in both hemispheres. We also observed a distinct spatial organization of cortical sites in the right STG, with dissonant-sensitive sites located anterior to non-sensitive sites. In sum, these findings demonstrate differential processing of consonance and dissonance in bilateral STG with the right hemisphere exhibiting robust and spatially organized sensitivity toward dissonance.