Clinical Outcomes and Quality of Life in Patients Submitted to Electroconvulsive Therapy
Clinical Outcomes and Quality of Life in Patients Submitted to Electroconvulsive Therapy
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DOI：
10.1097/yct.0b013e318190b2a9
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发表时间：
2009-09-01
期刊：
影响因子：
2.5
通讯作者：
Fleck, Marcelo P.
中科院分区：
文献类型：
--
作者：
Antunes, Paula Barros;Fleck, Marcelo P.
目的：本研究旨在评价电休克治疗(ECT)对阿雷格里港医院住院患者临床症状和生活质量的改善作用，并比较患者和医生的心理病理指标。方法：采用纵向观察性研究，对58例接受ECT治疗的患者在治疗前和治疗后24小时的临床症状和生活质量进行评估。使用行为与症状识别量表32(BASE-32)、简明精神病学评定量表(BPRS-A)和临床总体印象(CGI)对症状进行评估。结果：58例患者中，25例(43.1%)为重度抑郁，23例(39.7%)为双相情感障碍。47例(81.1%)患者因难治性抑郁而行电休克治疗。治疗前后BASIC-32、BPRS-A、CGI评分及WHOQOL各维度均有显著差异(P<；0.001)，其中生理和心理领域的差异大于社会关系和环境领域。BASE-32量表和BASE-32量表的量效相似。结论：电惊厥治疗与精神障碍患者的症状和生活质量的改善有关，这可以从医生(BPRS和CGI)和患者(WHOQOL和BASE-32)的测量中看出。病人和医生的观点有相似之处。
Objectives: The aims of this study were to evaluate the effect of electroconvulsive therapy (ECT) on clinical and quality of life improvement in patients hospitalized at the Hospital de Clinicas de Porto Alegre and to compare psychopathology measures between the patient's and the physician's perspectives.Methods: In a longitudinal and observational study, 58 patients who submitted to ECT ere assessed for clinical symptoms and quality of life before and 24 hours after treatment. Symptoms were assessed using the Behavior and Symptom Identification Scale 32 (BASIS-32), Brief Psychiatry Rating Scale-Anchored (BPRS-A), and Clinical Global Impression (CGI). Quality of life was assessed using the World Health Organization Quality of Life-Bref (WHOQOL-BREF) assessment.Results: Of 58 patients assessed, 25 (43.1%) had major depression and 23 (39.7%) had bipolar disorder. Electroconvulsive therapy was indicated because of resistant depression in 47 patients (81.1%). There was a significant difference (P < 0.001) between the periods before and after ECT in BASIS-32, BPRS-A, and CGI scores and in all WHOQOL domains, with greater difference in physical and psychological domains than in social relationships and environment. Size effects of BASIS-32 and BPRS scales were similar.Conclusion: Electroconvulsive therapy is associated with improvement in symptoms and in quality of life of patients with psychiatric disorders, which could be seen in measurements assessed by physicians (BPRS and CGI) and by patients (WHOQOL and BASIS-32). There was similarity between the patient's and the physician's perspectives.