Skin peeling syndrome in a Kurdish family.
Skin peeling syndrome in a Kurdish family.
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DOI：
10.1001/archderm.1985.01660040129027
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发表时间：
1985-04
影响因子：
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通讯作者：
S. Hacham‐Zadeh;K. Holubar
中科院分区：
文献类型：
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作者：
S. Hacham‐Zadeh;K. Holubar
皮肤脱皮综合征(SPS)是一种罕见的遗传性皮肤病，发病年龄从出生到成年不等。2临床上，它的特征是皮肤出现瘙痒或非瘙痒的自发性浅表脱皮，有时伴有红斑或水泡。2皮肤通常受累，但在一些患者头皮、面部、手掌和脚底可能不受影响。2季节性变化已有报道。2，3组织学特征是角质层和颗粒层之间的表皮分离。3我们描述了一个起源于库尔德兰的犹太家庭的兄弟姐妹，他们都受到了SPS的影响。病例1报告-先证者，一名8岁男孩，因皮肤瘙痒、发红和脱皮而被转诊至皮肤诊所。出生四天后，他的脖子、肘关节前部、肘部和手腕开始发红，脱皮；后来，发红和脱皮。
Skin peeling syndrome (SPS) is a rare genodermatosis, with variable age of onset from birth1to adulthood.2Clinically, it is characterized by a pruritic or nonpruritic spontaneous superficial peeling of the skin, which sometimes is accompanied by erythema or vesiculation.2The skin involvement is usually general, but in some patients the scalp, face, palms, and soles may be unaffected.2Seasonal changes have been reported.2,3The histologic picture is characterized by separation of the epidermis between the stratum corneum and the stratum granulosum.3We describe herein two siblings of a Jewish family originating from Kurdistan who were affected by SPS. Report of Cases Case 1.— The proband, an 8-year-old boy, was referred to the skin clinic for itching, redness, and peeling of the skin. Redness, peeling of the neck, antecubital and popliteal areas, and wrists, developed four days after his birth; later on, redness and peeling