Speech synthesis technologies for individuals with vocal disabilities: Voice banking and reconstruction
Speech synthesis technologies for individuals with vocal disabilities: Voice banking and reconstruction
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适用于声乐障碍人士的语音合成技术：语音银行和重建
DOI：
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
S. Renals
中科院分区：
文献类型：
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作者：
J. Yamagishi;C. Veaux;Simon King;S. Renals
在这篇特邀论文中，我们概述了语音合成技术的临床应用，并解释了一些选定的研究。我们还介绍了爱丁堡大学针对运动神经元疾病和帕金森病等退行性疾病患者的新项目“语音银行和重建”，并展示了语音合成技术如何改善患者的生活质量。 1.1.言语障碍和障碍 言语障碍有多种原因。导致严重言语障碍的主要神经退行性疾病包括运动神经元疾病（MND）、帕金森病和多发性硬化症；导致此类疾病的非进行性病症包括中风和脑瘫。言语障碍也可能由声带癌等疾病引起，从而导致喉切除术。 MND 在美国也称为肌萎缩侧索硬化症 (ALS) 或卢伽雷氏病，是一种使人衰弱的神经系统疾病，由大脑和脊髓中的大运动神经元退化和死亡引起。这会导致肌肉无力恶化，导致行动能力丧失以及吞咽、呼吸和言语困难。大约 75% 的 MND 患者在死亡时无法说话[1]。 MND 有四种类型。大多数 ALS 和进行性延髓麻痹病例发生在 60 岁以上。原发性侧索硬化症的发病年龄为五十岁。进行性肌萎缩症的发病年龄通常在五十岁以下。英国苏格兰每年诊断出约 100 例新的 MND 病例。
In this invited paper, we overview the clinical applications of speech synthesis technologies and explain a few selected researches. We also introduce the University of Edinburgh’s new project ‘‘Voice Banking and reconstruction’’ for patients with degenerative diseases, such as motor neurone disease and Parkinson’s disease and show how speech synthesis technologies can improve the quality of life for the patients. 1.1. Speech Disorder and Impairment Speech disorders have a variety of causes. The major neurological degenerative diseases resulting in severe speech disorders include Motor Neurone Disease (MND), Parkinson’s, and Multiple Sclerosis; non-progressive conditions resulting in such disorders include Stroke and Cerebral Palsy. Speech impairment may also be caused by conditions such as cancer of the vocal cords, resulting in laryngectomy. MND, also known in the USA as Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s disease, is a debilitating neurological disease that results from the degeneration and death of the large motor neurones in the brain and spinal cord. This causes a worsening muscle weakness that leads to loss of mobility and difficulties with swallowing, breathing and speech production. Approximately 75% of MND patients are unable to speak by the time of their death [1]. There are four types of MNDs. Most cases of ALS and Progressive Bulbar Palsy are recorded in over 60’s. Age of onset of Primary Lateral Sclerosis is fifty years. Age of onset of Progressive Muscular Atrophy is usually under fifty years. About 100 new cases of MND are diagnosed in Scotland, U.K. each year.