Pulsatile secretion of gonadotrophins, ovarian steroids and ovarian oxytocin during prostaglandin-induced regression of the corpus luteum in the cow.
Pulsatile secretion of gonadotrophins, ovarian steroids and ovarian oxytocin during prostaglandin-induced regression of the corpus luteum in the cow.
复制标题
在前列腺素诱导的牛黄体退化过程中，促性腺激素、卵巢类固醇和卵巢催产素的脉动分泌。
DOI：
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
D. L. Walters
中科院分区：
文献类型：
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作者：
E. Schallenberger;D. Schams;B. Bullermann;D. L. Walters
在发情周期第12天，对5头小母牛给予溶黄体剂量（500 μ g）的氯前列烯醇。在注射PG后的-6至0（对照期）、0至12和24至36 h，以5-20 min的间隔从尾腔静脉和颈静脉同时采集血液样品。在所有采样期间，LH脉冲与FSH脉冲同时分泌。然而，在对照期间，检测到单独的FSH脉冲，导致FSH的脉冲间期短于LH（P <0.01）（93 vs 248 min）。LH和FSH脉冲频率增加（P <0.01），从PG后1-3小时开始，脉冲间隔分别为59和63分钟，并在PG后24-36小时继续保持。同时，LH（但不是FSH）的基础浓度和脉冲幅度增加2-3倍（P <0.01）。3头小母牛在PG后24-36 h FSH基础浓度和脉冲幅度降低（P <0.05）。分别在PG后4-12 h（3头小母牛）和24-36 h（2头小母牛）期间观察到雌二醇的脉冲分泌频率与LH相似，导致平均雌二醇浓度较高（P <0.05）。PG后5-10 min，腔静脉中孕酮浓度升高（P <0.01），20 min下降（P <0.01）67%，PG后2-3 h开始升高（P <0.05），平均持续3.3h。（400字处删节）
A luteolytic dose (500 micrograms) of cloprostenol was given on Day 12 of the oestrous cycle to 5 heifers. Blood samples were collected simultaneously from the caudal vena cava and jugular vein at 5-20-min intervals from -6 to 0 (control period), 0 to 12 and 24 to 36 h after PG injection. Pulses of LH were secreted concomitantly with pulses of FSH during all sampling periods. However, during the control period separate FSH pulses were detected resulting in a shorter (P less than 0.01) interpulse interval for FSH than LH (93 versus 248 min). LH and FSH pulse frequencies increased (P less than 0.01) beginning 1-3 h after PG to interpulse intervals of 59 and 63 min, respectively, and continued to be maintained 24-36 h after PG. Concomitantly there was a 2-3-fold increase (P less than 0.01) in basal concentrations and pulse amplitude for LH (but not FSH). FSH basal concentrations and pulse amplitudes decreased (P less than 0.05) in 3 heifers 24-36 h after PG. Pulsatile secretion of oestradiol was observed at frequencies similar to LH during the periods 4-12 h (3 heifers) and 24-36 h (2 heifers) after PG, respectively, resulting in higher (P less than 0.05) mean oestradiol concentrations. Progesterone concentrations in the vena cava increased (P less than 0.01) 5-10 min after PG but decreased (P less than 0.01) 67% by 20 min after PG. This decrease was followed by a rise (P less than 0.05) beginning 2-3 h after PG and lasting for an average of 3.3 h.(ABSTRACT TRUNCATED AT 400 WORDS)