Psychiatric and medical correlates of DSM-5 eating disorders in a nationally representative sample of adults in the United States
Psychiatric and medical correlates of DSM-5 eating disorders in a nationally representative sample of adults in the United States
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DOI：
10.1002/eat.23004
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发表时间：
2019-01-01
影响因子：
5.5
通讯作者：
Grilo, Carlos M.
中科院分区：
文献类型：
--
作者：
Udo, Tomoko;Grilo, Carlos M.
目的研究精神和躯体相关的DSM-5进食障碍（ED）-神经性厌食症（AN），神经性贪食症（BN），暴食症（BED）-在美国的全国代表性样本的成年人。方法：在全国酒精和相关疾病流行病学调查III（NESARC-III）中，36，309名成年参与者完成了结构化诊断访谈（AUDADIS-5），以确定精神疾病，包括ED，并报告了12个月的慢性躯体疾病诊断。计算AN、BN和B艾德组和第四组无特异性艾德的终生精神疾病和躯体疾病的患病率;多元logistic回归模型比较了每种特异性艾德与非特异性艾德组的精神/躯体疾病的可能性。结果三种ED均与终生心境障碍、焦虑障碍、酒精和药物使用障碍以及人格障碍显著相关。在所有三个ED中，重度抑郁症是最普遍的，其次是酒精使用障碍。AN与纤维肌痛、癌症、贫血和骨质疏松症显著相关，而BED与糖尿病、高血压、高胆固醇和甘油三酯显著相关。BN与任何躯体疾病均无显著相关性。结论：本研究在一个大的代表性美国成年人样本中研究了DSM-5 AN、BN和BED的终身精神和躯体相关性。我们的研究结果与其他精神疾病和目前的慢性躯体疾病的显着关联表明ED的严重负担。我们的研究结果表明，在特定的ED之间存在重要差异，并表明与以前基于早期诊断标准的小型研究存在一些相似性和差异。
Objective To examine psychiatric and somatic correlates of DSM-5 eating disorders (EDs)-anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED)-in a nationally representative sample of adults in the United States. Method A national sample of 36,309 adult participants in the national epidemiologic survey on alcohol and related conditions III (NESARC-III) completed structured diagnostic interviews (AUDADIS-5) to determine psychiatric disorders, including EDs, and reported 12-month diagnosis of chronic somatic conditions. Prevalence of lifetime psychiatric disorders and somatic conditions were calculated across the AN, BN, and BED groups and a fourth group without specific ED; multiple logistic regression models compared the likelihood of psychiatric/somatic conditions with each specific ED relative to the no-specific ED group. Results All three EDs were associated significantly with lifetime mood disorders, anxiety disorders, alcohol and drug use disorders, and personality disorders. In all three EDs, major depressive disorder was the most prevalent, followed by alcohol use disorder. AN was associated significantly with fibromyalgia, cancer, anemia, and osteoporosis, and BED with diabetes, hypertension, high cholesterol, and triglycerides. BN was not associated significantly with any somatic conditions. Conclusions This study examined lifetime psychiatric and somatic correlates of DSM-5 AN, BN, and BED in a large representative sample of U.S. adults. Our findings on significant associations with other psychiatric disorders and with current chronic somatic conditions indicate the serious burdens of EDs. Our findings suggest important differences across specific EDs and indicate some similarities and differences to previous smaller studies based on earlier diagnostic criteria.