Dependence of the signal amplification potential of colloidal gold nanoparticles on resonance wavelength in surface plasmon resonance-based detection.
Dependence of the signal amplification potential of colloidal gold nanoparticles on resonance wavelength in surface plasmon resonance-based detection.
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DOI：
10.1016/j.aca.2007.07.056
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发表时间：
2007-09
影响因子：
6.2
通讯作者：
Elain Fu;S. A. Ramsey;P. Yager
中科院分区：
文献类型：
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作者：
Elain Fu;S. A. Ramsey;P. Yager
在基于表面等离子体共振（SPR）的检测中，我们展示了胶体金纳米颗粒吸附在平面金表面上的共振波长依赖信号。实验测量了SPR信号作为粒子表面覆盖的函数，给出了三种不同的共振波长。胶体金纳米粒子产生的SPR信号在650、770nm和920nm的共振波长范围内变化。实验所得的SPR曲线与洛伦兹吸光度模型的结果在较低的颗粒表面覆盖率下一致。结果表明，对于所探索的实验条件的子集，信号差异几乎是两倍。
We demonstrate the resonance wavelength-dependent signal of colloidal gold nanoparticles adsorbed to a planar gold surface in surface plasmon resonance (SPR)-based detection. Experimental measurements of the SPR signal as a function of particle surface coverage are presented for three different resonance wavelengths. The SPR signal due to the colloidal gold nanoparticles varies across the resonance wavelengths of 650nm, 770nm, and 920nm. The experimental SPR curves show good agreement with the results of a Lorentz absorbance model at the lower particle surface coverages investigated. The results demonstrate an almost twofold signal difference for a subset of the experimental conditions explored.