Basal forebrain lesions alter stimulus-evoked metabolic activity in rat somatosensory cortex
Basal forebrain lesions alter stimulus-evoked metabolic activity in rat somatosensory cortex
复制标题
基底前脑损伤改变大鼠体感皮层刺激诱发的代谢活动
DOI:
10.1016/0006-8993(91)91256-z
复制
发表时间:
1991
期刊:
影响因子:
2.9
通讯作者:
S. Juliano
中科院分区:
文献类型:
--
作者:
S. E. Jacobs;R. A. Code;S. Juliano
Acetylcholine (ACh) has been suggested to play a crucial role in normal cortical functioning. To assess the impact of cortical ACh depletion on metabolic activity in the barrel field of rat somatosensory cortex, unilateral lesions of the basal forebrain were made. One to 9 weeks later, a 2-deoxyglucose experiment was conducted. Stimulus-evoked metabolic activity in the barrel field ipsilateral to the lesion was significantly reduced compared with the contralateral side. These results suggest that ACh plays a significant role in processing stimulus-evoked sensory information.
DOI:
--
发表时间:
1985
期刊:
Biomedical sciences instrumentation
影响因子:
--
作者:
Tommerdahl,M;Baker,R;Whitsel,B;Juliano,S
通讯作者:
Juliano,S
影响因子:
2.5
作者:
Metherate,R;Tremblay,N;Dykes,RW
通讯作者:
Dykes,RW
影响因子:
2.5
作者:
Metherate,R;Tremblay,N;Dykes,RW
通讯作者:
Dykes,RW