EMT twists the road to PI3K.

EMT twists the road to PI3K.
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DOI:
10.1158/2159-8290.cd-13-1030
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发表时间:
2014-02
期刊:
影响因子:
28.2
通讯作者:
Benes CH
Benes CH
中科院分区:
医学1区
文献类型:
--
作者:
Niederst MJ;Benes CH

文献摘要

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上皮间质转化(EMT)对许多发育事件很重要,并与肿瘤扩散和治疗耐药性有关。Salt及其同事确定了EMT如何影响非小细胞肺癌中增殖信号如何流向PI3激酶。
Epithelial to Mesenchymal Transition (EMT) is important for many developmental events and has been linked to tumor dissemination and therapeutic resistance. Salt and colleagues identify how EMT impacts how proliferation signals flow to PI3 kinase in non-small cell lung cancer.