“Eating, laughing, and tonic seizing”, that is a laughter‐induced syncope in elderly
“Eating, laughing, and tonic seizing”, that is a laughter‐induced syncope in elderly
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“食、笑、补夺”，即老年人笑致晕厥
DOI：
10.1111/ncn3.12474
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发表时间：
2020
影响因子：
0.4
通讯作者：
Ikeda Akio
中科院分区：
文献类型：
--
作者：
Honda Masayuki;Shimotake Akihiro;Hitomi Takefumi;Kuzuya Akira;Takahashi Ryosuke;Ikeda Akio
笑声诱发的晕厥是一种罕见的综合征，预后良好，但卫生保健提供者并不广泛了解。我们有一个病人在吃饭时大笑后立即出现全身“冻结”。排除癫痫，诊断为笑诱发性晕厥。严重的脑灌注不足和相对不受抑制的脑干功能可以解释强直性姿势。对大笑后出现全身“冻结”发作的患者，应与强直性发作、痉挛性发作和痉挛性发作沿着，作为鉴别诊断。详细而准确的询问有助于正确诊断，并可避免不必要的抗癫痫药物的重复使用。
Laughter‐induced syncope is a rare syndrome with good prognosis, but not widely known by health care providers. We had a patient who had whole body “freezing” episodes immediately after laughing vigorously during meals. Epilepsy was ruled out and diagnosis of laughter‐induced syncope was made. Severe cerebral hypoperfusion and relatively disinhibited brain stem function may account for tonic posturing. It should be considered as a differential diagnosis in patients presenting whole body “freezing” episodes after big laughter, along with tonic seizure, gelastic seizure and cataplexy. Detailed and precise inquiry is helpful in correct diagnosis and could prevent from repeated events with unnecessary antiseizure medication.