Detection of cardio-metabolic risk by BMI and waist circumference among a population of Guatemalan adults.
Detection of cardio-metabolic risk by BMI and waist circumference among a population of Guatemalan adults.
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通过 BMI 和腰围检测危地马拉成年人群的心脏代谢风险。
DOI：
10.1017/s1368980007001504
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发表时间：
2008
影响因子：
3.2
通讯作者：
Stein,AryehD
中科院分区：
文献类型：
--
作者：
Gregory,CriaO;Corvalán,Camila;Ramirez-Zea,Manuel;Martorell,Reynaldo;Stein,AryehD
背景BMI和腰围（WC）用于筛查心脏代谢风险;然而，目前尚不清楚这些指标在儿童发育迟缓人群中的表现如何。目的评估BMI和WC作为心脏代谢风险指标，并确定1325名危地马拉成年人的最佳临界点（44%发育不良：≤150 cm的妇女;方法高脂血症的危险因素为收缩压/舒张压≥130/≥85 mmHg，血糖≥ 5.5mmol/l，TAG ≥ 1.7mmol/l，总胆固醇/高密度脂蛋白胆固醇≥ 5.0，以及存在两个或更多个和三个或更多个前述危险因素。结果男性BMI和WC的ROC曲线下面积分别为0.59 ~ 0.77和0.59 ~ 0.78，女性分别为0.66 ~ 0.72和0.64 ~ 0.72。BMI的最佳临界点在男性中为24.7 - 26.1 kg/m2（24.5 - 26.1 kg/m2发育迟缓; 24.8 - 26.3 kg/m2非发育迟缓），在女性中为26.5 - 27.6 kg/m2（26.3 - 27.8 kg/m2发育迟缓; 26.6 - 27.9 kg/m2非发育迟缓）。男性腰围的最佳分界点为87·3-91·1 cm（发育迟缓85·3-89·4 cm;非发育迟缓88·5-93·3 cm），女性腰围的最佳分界点为91·3-95·3 cm（发育迟缓90·9-94·4 cm;非发育迟缓91·8-95·6 cm）。发育迟缓男性的最佳WC临界点比非发育迟缓男性低几厘米，两者都大大低于西方人群目前的建议。从西方人口中得出的分界点可能不适合发育迟缓发生率高的发展中国家。
BackgroundBMI and waist circumference (WC) are used to screen for cardio-metabolic risk; however it is unclear how well these indices perform in populations subject to childhood stunting.ObjectivesTo evaluate BMI and WC as indicators of cardio-metabolic risk and to determine optimal cut-off points among 1325 Guatemalan adults (44 % stunted: ≤150 cm women; ≤162 cm men).MethodsCardio-metabolic risk factors were systolic/diastolic blood pressure ≥130/≥85 mmHg, glucose ≥5·5 mmol/l, TAG ≥1·7 mmol/l, ratio of total cholesterol to HDL-cholesterol ≥5·0, and the presence of two or more and three or more of the preceding risk factors. Receiver operating characteristic (ROC) curve analysis was used.ResultsAreas under the ROC curve were in the range of 0·59–0·77 for BMI and 0·59–0·78 for WC among men and 0·66–0·72 and 0·64–0·72 among women, respectively. Optimal cut-off points for BMI were 24·7–26·1 kg/m2 among men (24·5–26·1 kg/m2 stunted; 24·8–26·3 kg/m2 non-stunted) and 26·5–27·6 kg/m2 among women (26·3–27·8 kg/m2 stunted; 26·6–27·9 kg/m2 non-stunted). Optimal cut-off points for WC were 87·3–91·1 cm among men (85·3–89·4 cm stunted; 88·5–93·3 cm non-stunted) and 91·3–95·3 cm among women (90·9–94·4 cm stunted; 91·8–95·6 cm non-stunted).ConclusionOptimal cut-off points for BMI were slightly higher among women than men with no meaningful differences by stature. Optimal cut-off points for WC were several centimetres lower for stunted compared with non-stunted men, and both were substantially lower than the current recommendations among Western populations. Cut-off points derived from Western populations may not be appropriate for developing countries with a high prevalence of stunting.