GPU accelerated real-time multi-functional spectral-domain optical coherence tomography system at 1300 nm.
GPU accelerated real-time multi-functional spectral-domain optical coherence tomography system at 1300 nm.
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DOI：
10.1364/oe.20.014797
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发表时间：
2012-07-02
期刊：
影响因子：
3.8
通讯作者：
Park BH
中科院分区：
文献类型：
--
作者：
Wang Y;Oh CM;Oliveira MC;Islam MS;Ortega A;Park BH
我们提出了一种 GPU 加速的 1300nm 多功能谱域光学相干断层扫描系统。该系统能够实时处理和显示每个强度图像，由以每秒 20 帧采集的 512 像素 x 2048 A 线组成。所有四个尺寸为 512 像素 x 2048 A 线的图像（强度、相位延迟、流动和正面视图）的更新速率约为每秒 10 帧。此外，我们首次报告了由一组堆叠的偏振膜和波片组成的样品的相位延迟和衰减特性。计算出的光轴方向、相位延迟和衰减与预期值吻合良好。通过对鲎侧面复眼、不均匀加热的鸡肌肉和微流体装置进行成像，分别演示了多功能 OCT CPU-GPU 混合采集系统各个方面的速度、强度、相位延迟和流量。对具有薄颅骨准备的小鼠大脑进行体内成像，并展示了该系统进行实时多功能 OCT 可视化的能力。
We present a GPU accelerated multi-functional spectral domain optical coherence tomography system at 1300nm. The system is capable of real-time processing and display of every intensity image, comprised of 512 pixels by 2048 A-lines acquired at 20 frames per second. The update rate for all four images with size of 512 pixels by 2048 A-lines simultaneously (intensity, phase retardation, flow and en face view) is approximately 10 frames per second. Additionally, we report for the first time the characterization of phase retardation and diattenuation by a sample comprised of a stacked set of polarizing film and wave plate. The calculated optic axis orientation, phase retardation and diattenuation match well with expected values. The speed of each facet of the multi-functional OCT CPU-GPU hybrid acquisition system, intensity, phase retardation, and flow, were separately demonstrated by imaging a horseshoe crab lateral compound eye, a non-uniformly heated chicken muscle, and a microfluidic device. A mouse brain with thin skull preparation was imaged in vivo and demonstrated the capability of the system for live multi-functional OCT visualization.