MICROWAVE IRRADIATION INCREASES RECOVERY OF NEUROPEPTIDES FROM BRAIN-TISSUES
MICROWAVE IRRADIATION INCREASES RECOVERY OF NEUROPEPTIDES FROM BRAIN-TISSUES
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DOI：
10.1016/0196-9781(90)90151-t
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发表时间：
1990-11-01
期刊：
影响因子：
3
通讯作者：
MATHE, AA
中科院分区：
文献类型：
--
作者：
THEODORSSON, E;STENFORS, C;MATHE, AA
研究了聚焦高能微波处理（MW）对脑内P物质、神经激肽A、神经肽Y、神经紧张素、甘丙氨酸和降钙素基因相关肽的浓度和分子形态的影响。各组大鼠按以下方式处理：1)MW， 22℃贮存60 min， 2)斩首，22℃贮存60 min， 3)斩首，22℃贮存60 min， MW处理，4)MW，斩首，22℃贮存2 min， 5)斩首，22℃贮存2 min。在所有情况下，肽浓度在MW牺牲组最高。MW通过快速抑制肽酶活性和增加肽的溶解度/可提取性来增加完整肽的浓度。
The effect of focused high energy microwave treatment (MW) on brain concentrations and molecular forms of substance P, neurokinin A, neuropeptide Y, neurotensin, galanin and calcitonin gene-related peptide was investigated. Groups of rats were treated as follows: 1) MW, storage for 60 min ad 22-degrees-C, 2) Decapitation, storage for 60 min at 22-degrees-C, 3) Decapitation, storage for 60 min at 22-degrees-C, MW treatment, 4) MW, decapitation, storage for 2 min at 22-degrees-C and 5) Decapitation, storage for 2 min at 22-degrees-C. Peptide concentrations were in all instances highest in the MW sacrificed groups. MW increased the concentration of intact peptides by rapid inhibition of peptidase activity and increase in peptide solubility/extractability.