Applicability of flow cytometry in breast cancer.
Applicability of flow cytometry in breast cancer.
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流式细胞术在乳腺癌中的应用。
DOI：
10.1111/j.1749-6632.1993.tb38792.x
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发表时间：
1993
影响因子：
5.2
通讯作者：
Clark,GM
中科院分区：
文献类型：
--
作者：
Clark,GM
越来越多的证据表明，流式细胞术可以提供有关乳腺肿瘤行为的重要信息。该技术的一个特别吸引人的方面是能够确定新鲜手术标本、冷冻活检标本和档案石蜡包埋块的流式细胞术参数。然而，在流式细胞术被广泛应用之前，关于组织制备和细胞周期分析的标准化问题必须得到解决。目前正在讨论质量控制标准，这将有助于减少实验室间的差异，特别是关于s相分数的绝对值。
The cumulative evidence indicates that flow cytometry can provide important information about the behavior of breast tumors. A particularly appealing aspect of this technology is the ability to determine flow cytometric parameters on fresh surgical samples, frozen biopsy specimens, and archival paraffin-embedded blocks. However, several issues regarding the standardization of tissue preparation and the cell cycle analyses must be addressed before flow cytometry can be routinely applied on a wide scale. Quality control standards are currently being discussed that will help to reduce interlaboratory variability, particularly with respect to absolute values of S-phase fraction.