Behavioral readout of spatio-temporal codes in olfaction
Behavioral readout of spatio-temporal codes in olfaction
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DOI：
10.1016/j.conb.2018.04.008
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发表时间：
2018-10-01
影响因子：
5.7
通讯作者：
Rinberg, Dmitry
中科院分区：
文献类型：
--
作者：
Chong, Edmund;Rinberg, Dmitry
以越来越大的规模和分辨率进行的神经记录揭示了嗅觉系统中复杂的、时空精确的活动模式。多个模型可以解释时空嗅觉代码的功能后果，但与行为的联系仍然不清楚。最近的证据表明，在该领域的行为的敏感性，在代码中的精细空间和时间的功能。这些特征和特征的组合如何引起嗅觉行为是该领域积极研究的主题。现代遗传学和光遗传学方法在测试嗅觉密码与行为之间的联系方面显示出巨大的潜力。
Neural recordings performed at an increasing scale and resolution have revealed complex, spatio-temporally precise patterns of activity in the olfactory system. Multiple models may explain the functional consequences of the spatio-temporal olfactory code, but the link to behavior remains unclear. Recent evidence in the field suggests a behavioral sensitivity to both fine spatial and temporal features in the code. How these features and combinations of features give rise to olfactory behavior is the subject of active research in the field. Modern genetic and optogenetic methods show great promise in testing the link between olfactory codes and behavior.