Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant
Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant
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DOI：
10.1093/ofid/ofv078
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发表时间：
2015-03-01
影响因子：
4.2
通讯作者：
Rodriguez, J. Martin
中科院分区：
文献类型：
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作者：
Stripling, Joshua;Kumar, Ranjit;Rodriguez, J. Martin
我们报告了在患有复发性艰难梭菌、耐万古霉素肠球菌 (VRE) 粪便优势和复发性 VRE 感染的单个心肾移植受者中使用粪便微生物群移植的情况。粪便微生物群移植导致了多样化微生物群的重建，其中（1）艰难梭菌和 VRE 的相对丰度降低，以及（2）积极的临床结果。
We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.