A pilot study of a weight management program with food provision in schizophrenia
A pilot study of a weight management program with food provision in schizophrenia
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DOI：
10.1016/j.schres.2007.05.022
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发表时间：
2007-11-01
影响因子：
4.5
通讯作者：
Wexler, Bruce E.
中科院分区：
文献类型：
--
作者：
Jean-Baptiste, Michel;Tek, Cenk;Wexler, Bruce E.
肥胖是一个严重的医学问题，严重影响着患有严重精神疾病的人。旨在改变生活方式的行为策略已被证明对一般人群的减肥有效，但尚未对精神分裂症患者进行充分的研究。我们进行了一项已建立的减肥计划的随机对照试验，针对这一特定人群进行了修改，并辅以一项新的食物替代计划，以及实用的、基于社区的购物和准备健康食品的教学。该计划不仅阻止了体重增加，并产生了有意义的体重减轻，而且在干预完成后6个月体重持续下降。认知障碍与参与者从该计划中获益的程度无关。综上所述，设计良好的简单行为方案可以为精神分裂症合并合并肥胖患者带来持久的体重减轻，改善代谢指标，并可能降低与肥胖相关的重大医疗风险。(C) 2007年Elsevier B.V.出版
Obesity is a serious medical problem that disproportionately affects people with severe mental illness. Behavioral strategies aimed at lifestyle modification have proven effective for weight loss in general population but have not been studied adequately among persons with schizophrenia. We have conducted a randomized controlled pilot trial of an established weight loss program, modified for this specific population, and supplemented with a novel food replacement program, as well as practical, community based teaching of shopping and preparing healthy food. The program not only arrested weight gain, and produced meaningful weight loss, but also weight loss continued 6 months after the intervention is completed. Cognitive impairment bad no bearing to the extent a participant benefited from the program. As a conclusion, well designed simple behavioral programs can produce lasting weight loss for patients with schizophrenia and comorbid obesity, improve metabolic indices, and possibly decrease significant medical risks associated with obesity. (C) 2007 Published by Elsevier B.V.