Epidemiological Survey of Border Disease Virus among Sheep from Northern Districts of Japan
Epidemiological Survey of Border Disease Virus among Sheep from Northern Districts of Japan
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DOI：
10.1292/jvms.11-0072
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发表时间：
2011-12-01
影响因子：
1.2
通讯作者：
Harasawa, Ryo
中科院分区：
文献类型：
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作者：
Giangaspero, Massimo;Ibata, Georgina;Harasawa, Ryo
日本首次对小反刍动物进行了边境病病毒（BDV）的流行病学调查。绵羊血清，采集自北海道的北方县。使用中和过氧化物酶连接抗体试验检查青森和岩手县是否存在抗BDV抗体。在165份样品中，29份（17.6%）为BDV血清阳性。结果具有专属性，不包括与牛病毒性腹泻病毒（BVDV）的交叉反应。仅1份样本（0.6%）为BVDV阳性，BDV阴性。尽管有病毒循环的血清学证据，但日本没有绵羊边界病的临床病例。虽然没有进行诊断措施，感染似乎并没有与母羊生育力的降低，也没有与羔羊死亡率。
The first epidemiological survey of Border disease virus (BDV) was undertaken in small ruminants in Japan. Ovine sera, collected from the northern prefectures of Hokkaido. Aomori and Iwate, were examined for the presence of antibodies against BDV using the neutralization peroxidase-linked antibody test. Twenty-nine (17.6%) of one hundred and sixty-five samples were seropositive for BDV. Results were specific, excluding cross-reactions with bovine viral diarrhea virus (BVDV). Only one sample (0.6%) was positive for BVDV, and was negative for BDV. Despite serological evidence of virus circulation, there have been no clinical cases of border disease in sheep in Japan. Although no diagnostic measures were performed, the infection did not appear to be associated with a reduction in ewe fertility nor with lamb mortality.