Acupuncture for chronic pain in adults with sickle cell disease: a mixed-methods pilot study.
Acupuncture for chronic pain in adults with sickle cell disease: a mixed-methods pilot study.
复制标题
DOI：
10.1177/09645284211017303
复制
发表时间：
2021-12
期刊：
影响因子：
--
通讯作者：
Schlaeger JM
中科院分区：
文献类型：
--
作者：
Li H;Patil CL;Molokie RE;Njoku F;Steffen AD;Doorenbos AZ;Schlaeger JM
慢性疼痛是镰状细胞病（SCD）患者的常见症状。我们的目的是评估的可行性和可接受性进行针灸治疗慢性疼痛的成人SCD。这是一项在6名成人SCD患者中进行的单组前瞻性初步研究。参与者报告慢性疼痛≥ 3个月，年龄> 18岁。根据方案，每周进行两次针灸治疗，持续5周，每次30分钟。所有治疗均在伊利诺伊大学芝加哥护理学院的针灸治疗实验室进行。在基线和干预后测量疼痛强度、疼痛干扰和其他症状。参与者在针灸干预后完成了半结构式访谈和协议接受性问卷。6名受试者（平均年龄52.5岁，6名黑人）入组。尽管该研究因COVID-19而暂停，并非所有参与者都完成了10个疗程的方案，但完成率很高，没有错过预约。一名参与者因与针灸无关的住院而未完成研究。未报告不良事件。在基线后4-5周完成干预时，所有参与者的疼痛强度和疼痛干扰均降低。方案可接受性问卷的平均可接受性评分为82%。针刺治疗成人SCD是可行的，也是可以接受的。本研究可用于指导一项更大规模的随机对照试验，以评估针刺对缓解成人SCD慢性疼痛的作用。NCT 04I56399（ClinicalTrials.gov）
Chronic pain is a common symptom experienced among patients with sickle cell disease (SCD). Our aims were to assess the feasibility and acceptability of performing acupuncture for the treatment of chronic pain in adults with SCD. This was a single-arm, prospective pilot study of six adults with SCD. Participants reported ≥ 3 months of chronic pain and were > 18 years of age. Per protocol, acupuncture was to be administered twice per week for 5 weeks, for 30 min per session. All treatments were performed in the acupuncture treatment laboratory at the University of Illinois Chicago College of Nursing. Pain intensity, pain interference, and other symptoms were measured at baseline and after the intervention. Participants completed a semi-structured interview and a protocol acceptability questionnaire after the acupuncture intervention. Six participants (mean age 52.5 years, six Black) were enrolled. Although the study was suspended due to COVID-19 and not all participants completed the 10-session protocol, completion rates were high with no missed appointments. One participant did not complete the study due to hospitalization unrelated to acupuncture. No adverse events were reported. At completion of the intervention at 4–5 weeks post-baseline, all participants had reduced pain intensity and pain interference. The mean acceptability score on the protocol acceptability questionnaire was 82%. It was feasible and acceptable to implement acupuncture in adults with SCD. This study can be used to guide a larger randomized controlled trial to evaluate the effect of acupuncture on reducing chronic pain in adults with SCD. NCT04I56399 (ClinicalTrials.gov)
登录
查看更多内容
DOI：
10.1016/j.jpain.2017.11.005
发表时间：
2018-05
期刊：
The journal of pain
影响因子：
--
作者：
Vickers AJ;Vertosick EA;Lewith G;MacPherson H;Foster NE;Sherman KJ;Irnich D;Witt CM;Linde K;Acupuncture Trialists' Collaboration
通讯作者：
Acupuncture Trialists' Collaboration
影响因子：
4.6
作者：
Wang Y;Lei J;Gupta M;Peng F;Lam S;Jha R;Raduenz E;Beitz AJ;Gupta K
通讯作者：
Gupta K
影响因子：
3.6
作者：
Mahmood, Laila A.;Reece-Stremtan, Sarah;Darbari, Deepika S.
通讯作者：
Darbari, Deepika S.
DOI：
10.1016/j.ajem.2017.07.037
发表时间：
2018-01
期刊：
The American journal of emergency medicine
影响因子：
--
作者：
Molokie RE;Montminy C;Dionisio C;Farooqui MA;Gowhari M;Yao Y;Suarez ML;Ezenwa MO;Schlaeger JM;Wang ZJ;Wilkie DJ
通讯作者：
Wilkie DJ
影响因子：
39.2
作者：
Smith, Wally R.;Penberthy, Lynne T.;Roseff, Susan D.
通讯作者：
Roseff, Susan D.