[Difference by sex and age of mercury concentration in red blood cells].
[Difference by sex and age of mercury concentration in red blood cells].
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[红细胞中汞浓度的性别和年龄差异]。
DOI：
10.1265/jjh.48.911
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
M. Futatsuka
中科院分区：
文献类型：
--
作者：
Mineshi Sakamoto;Atsuhiro Nakano;Hirokatsu Akagi;T. Kitano;M. Futatsuka
红细胞（RBC）中的汞浓度是暴露于甲基汞的人最有用的指标之一。1989年，在熊本县的一个城镇，对参加集体健康检查的1，253名成年人（男性511人，女性742人）进行了鱼类消费调查，研究了红细胞中汞浓度的性别和年龄差异。结果如下：1.红细胞汞浓度呈对数正态分布，男性高于女性。男性红细胞中汞浓度的几何平均值为28.5 ng/g（范围为5.6至71.0 ng/g），女性为20.4 ng/g（范围为3.7至70.4 ng/g），男性明显高于女性。随着年龄的增长，男性和女性红细胞中汞的浓度均呈下降趋势。2.红细胞中的汞浓度显着增加鱼的消费量为两种性别。男性饮酒者红细胞中汞浓度显著高于非饮酒者，女性红细胞中汞浓度随体重增加而显著增加。3.红细胞中的汞浓度在男性比女性高，随着年龄的增长，两性在一个恒定的鱼类消费水平的条件下下降。4.在食用相同数量鱼的夫妇中，丈夫的红细胞汞浓度明显高于妻子。这些结果表明，红细胞中的汞浓度是男性高于女性，随着年龄的增长，在一个恒定的鱼类消费水平下降。
The mercury concentration in red blood cells (RBCs) is one of the most useful indicators for people exposed to methylmercury. Sex- and age-related differences in mercury concentrations in red blood cells were studied by considering fish consumption in 1,253 adults (511 males and 742 females) participating in a mass health examination conducted in a town of Kumamoto Prefecture in 1989. The results were as follows: 1. The mercury concentrations in RBCs showed lognormal distributions for both sexes with a higher mode in males than in females. The geometric mean of the mercury concentrations in the RBCs was 28.5 ng/g (ranging from 5.6 to 71.0 ng/g) for males and 20.4 ng/g (ranging from 3.7 to 70.4 ng/g) for females and was significantly higher in males than in females. The mercury concentration in RBCs decreased with aging for both sexes. 2. The mercury concentrations in RBCs significantly increased with the amount of fish consumption for both sexes. The mercury concentrations in RBCs were significantly higher in drinkers than in non-drinkers for males and the concentrations increased significantly with body weight for females. 3. The mercury concentrations in RBCs were higher in males than in females and decreased with aging for both sexes under conditions of a constant level of fish consumption. 4. In couples who consumed same amount of fish, the mercury concentrations in RBCs were significantly higher in husbands than in wives. These results suggest that the mercury concentrations in RBCs are higher in males than in females and decreases with aging under a constant level of fish consumption.