Sensitivity and specificity of the StratusOCT for perimetric glaucoma
Sensitivity and specificity of the StratusOCT for perimetric glaucoma
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DOI：
10.1016/j.ophtha.2004.06.039
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发表时间：
2005-01-01
期刊：
影响因子：
13.7
通讯作者：
Katz, J
中科院分区：
文献类型：
--
作者：
Budenz, DL;Michael, A;Katz, J
设计：前瞻性横断面研究。参与者：109名正常青光眼患者和63名青光眼患者。测试：使用Stratus OCT对每名患者的一只眼进行快速RNFL扫描。主要观察指标：不同光学相干断层扫描(OCT)诊断青光眼患者VF缺陷的敏感度和特异度。次要结果指标：受试者操作特征曲线下面积(Arocs)。结果：青光眼组VF缺陷的严重程度分布在轻度(18例)、中度(21例)和重度(24例)。青光眼视野的平均偏差为-8.4分贝，标准偏差为6.0分贝，范围为-0.14~-28.0分贝。以RNFL平均厚度异常为标准的灵敏度和特异度
Purpose: To determine the sensitivity and specificity of measurements of the retinal nerve fiber layer (RNFL) using the StratusOCT in glaucoma subjects with visual field (VF) defects.Design: Prospective cross-sectional study.Participants: One hundred nine normal and 63 glaucoma subjects.Testing: Fast RNFL scans were performed in one eye of each patient using the StratusOCT.Main Outcome Measures: Sensitivity and specificity of different optical coherence tomography (OCT) criteria for identifying glaucoma subjects with glaucomatous VF defects.Secondary Outcome Measures: Areas under the receiver operating characteristic curves (AROCs) for various OCT parameters.Results: Severity of VF defects in the glaucoma group was distributed between mild (18 subjects), moderate (21 subjects), and severe (24 subjects). The average mean deviation of the glaucoma fields was -8.4 decibels (dB), with a standard deviation of 6.0 dB and a range from -0.14 to -28.0 dB. The sensitivity and specificity using a criterion of average RNFL thickness abnormal at the