A new binary compound for the production of 124I via the 124Te(p,n) 124I reaction
A new binary compound for the production of 124I via the 124Te(p,n) 124I reaction
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DOI：
10.1016/j.apradiso.2006.10.012
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发表时间：
2007-04-01
影响因子：
1.6
通讯作者：
Nickles, Robert J.
中科院分区：
文献类型：
--
作者：
Nye, Jonathon A.;Avila-Rodriguez, Miguel A.;Nickles, Robert J.
在低能回旋加速器上研究了碲化铝（Al_2Te_3）作为Te-124（p，n）I-124反应产生I-124的靶材料。高熔点和形成的玻璃状基质加热后提供了一个稳定的目标材料在辐照高达20 μ A的11 MeV的质子。与传统的TeO 2/6%Al2O3混合物相比，87%的碲质量分数和95%的碘分离产率导致显著更高的碘量。使用离子色谱法对蒸馏样品进行放射化学分析表明，该产品在弱缓冲溶液中保持碘化物形式。放射性碘产品中稳定的Te杂质在离子交换色谱纯化后小于0.5 μ g。获得了229 +/-18 μ Ci/μ A的平均厚靶产率，并且在18 μ A下进行3小时的典型生产运行在轰击结束时产生12 mCi。在每次照射和蒸馏循环后，靶材料的总损失约为2%。(c)2006爱思唯尔有限公司保留所有权利。
The binary compound, aluminum telluride (Al2Te3), was investigated as a target material for the production of I-124 by way of the Te-124(p,n)I-124 reaction on a low-energy cyclotron. The high melting point and formation of a glassy matrix upon heating provided a stable target material at irradiations up to 20 mu A of 11 MeV protons. The 87% tellurium mass fraction and 95% iodine separation yield led to significantly higher quantities of iodine compared to traditional TeO2/6%Al2O3 admixtures. Radiochemical analysis of distilled samples using ion chromatography showed that the product remained in the iodide form while supported in weak buffer solutions. Stable Te impurities in the radioiodine product were less than 0.5 mu g following purification by ion exchange chromatography. Average thick target yields of 229 +/- 18 mu Ci/mu A It were achieved, and typical production runs at 18 mu A for three hours yielded 12mCi at the end-of-bombardment. Total losses of the target material after each irradiation and distillation cycle were approximately 2%. (c) 2006 Elsevier Ltd. All rights reserved.