Motion compensation for intravascular ultrasound palpography
Motion compensation for intravascular ultrasound palpography
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DOI：
10.1109/tuffc.2006.1665075
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发表时间：
2006-07-01
影响因子：
3.6
通讯作者：
van der Steen, Antonius F. W. (Ton)
中科院分区：
文献类型：
--
作者：
Leung, K. Y. Esther;Baldewsing, Radjkumarsing (Radj) A.;van der Steen, Antonius F. W. (Ton)
冠状动脉易损斑块破裂是急性冠状动脉综合征的主要原因。大多数易损斑块由覆盖在动脉粥样硬化核心上的薄纤维帽组成。这些斑块可以使用血管内超声（IVUS）触诊来识别，该触诊通过在不同管腔内压力下交叉相关RF信号来测量径向应变。多个应变图像（即，部分脉搏波描记图）在每个心动周期被平均以产生更稳健的复合脉搏波描记图。然而，由于心脏活动引起的导管运动导致RF信号的未对准，并且因此导致部分脉搏波图的未对准，从而导致不太有效的应变估计。为了补偿平面内导管旋转和平移，我们设计了四种基于块匹配的方法。全局旋转块匹配（GRBM）和轮廓映射（CMAP）方法测量导管旋转，局部块匹配（LBM）和导管旋转和平移（CRT）估计局部组织区域的位移。这些方法被应用到9个体内回调收购，与20 MHz的相控阵换能器。我们发现，所有这些方法都显着增加了部分和复合睑图中的有效应变估计数（P <0.008）。最好的方法，LBM，达到平均增加17%和15%，分别。该方法的实施应改善来自IVUS触诊的信息，从而更好地检测易损斑块。
Rupture of vulnerable plaques in coronary arteries is the major cause of acute coronary syndromes. Most vulnerable plaques consist of a thin fibrous cap covering an atheromous core. These plaques can be identified using intravascular ultrasound (IVUS) palpography, which measures radial strain by cross-correlating RF signals at different intraluminal pressures. Multiple strain images (i.e., partial palpograms) are averaged per heart cycle to produce a more robust compounded palpogram. However, catheter motion due to cardiac activity causes misalignment of the RF signals and thus of the partial palpograms, resulting in less valid strain estimates. To compensate for in-plane catheter rotation and translation, we devised four methods based on block matching. The global rotation block matching (GRBM) and contour mapping (CMAP) methods measure catheter rotation, and local block matching (LBM) and catheter rotation and translation (CRT) estimate displacements of local tissue regions. These methods were applied to nine in vivo pullback acquisitions, made with a 20 MHz phased-array transducer. We found that all these methods significantly increase the number of valid strain estimates in the partial and compounded palpograms (P < 0.008). The best method, LBM, attained an average increase of 17% and 15%, respectively. Implementation of this method should improve the information coming from IVUS palpography, leading to better vulnerable plaque detection.