A comparison of postoperative morphometric and hemodynamic changes between saphenous vein and left internal mammary artery grafts.
A comparison of postoperative morphometric and hemodynamic changes between saphenous vein and left internal mammary artery grafts.
复制标题
隐静脉和左乳内动脉移植物术后形态和血流动力学变化的比较。
DOI：
10.14814/phy2.13487
复制
发表时间：
2017-11
影响因子：
2.5
通讯作者：
Huo Y
中科院分区：
文献类型：
--
作者：
Fan T;Feng Y;Feng F;Yin Z;Luo D;Lu Y;Xu Y;Tan W;Huo Y
There is higher long‐term failure of the saphenous vein graft (SVG) compared with the left internal mammary artery (LIMA) graft, which is affected by the hemodynamic environment. A comprehensive analysis of postoperative structure‐function changes is important to study the atherogenesis in the SVG. A comparison of morphometric and hemodynamic parameters was carried out between LIMA grafts and SVGs and between different time points postoperatively. Various parameters were obtained from the image reconstruction and flow simulation in patients, who underwent CT exams for ~1 year, 5 and 10 years after revascularization. Morphometric data showed a decrease in lumen size in the entire SVG and anastomosis of different patients in a sequence of ~1 year, 5 and 10 years postoperatively despite negligible changes of LIMA size. Computational results indicated the fourfold increased surface area ratio (SAR) of low time‐averaged wall shear stress (TAWSS) in the SVG and anastomosis at postoperative 10 years than that at postoperative ~1 year. The SAR of high TAWSS gradient (TAWSSG) at the distal anastomosis between SVG and coronary arteries was significantly higher (14 ± 9% vs. 6 ± 8%) than that in the LIMA group at postoperative ~1 year. There were strong correlations between morphometric and hemodynamic parameters in the SVG and distal anastomosis at various time points postoperatively, which showed deterioration relevant to persistent diffuse diseases at postoperative ~10 years.
