CT colonography: multiobserver diagnostic performance.
CT colonography: multiobserver diagnostic performance.
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CT 结肠成像：多观察者诊断性能。
DOI：
10.1148/radiol.2252011625
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发表时间：
2002
期刊：
影响因子：
19.7
通讯作者：
Littenberg,Benjamin
中科院分区：
文献类型：
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作者：
McFarland,ElizabethG;Pilgram,ThomasK;Brink,JamesA;McDermott,RonanA;Santillan,CynthiaV;Brady,PatrickW;Heiken,JayP;Balfe,DennisM;Weinstock,LeonardB;Thyssen,ErikP;Littenberg,Benjamin
目的：前瞻性地评估多观察者诊断性能和读者的协议，结直肠息肉检测在一个特征良好的队列中的患者息肉数量增加，与平均风险的患者相比，结肠镜检查作为参考standard.MATERIALS和METHODS：一个队列的70例患者怀疑有息肉进行了检查与螺旋计算机断层扫描（CT）结肠成像，结肠镜检查进行的同一天。经直肠充气后，采用单排CT（5 mm准直，8 mm扫描床增量，2 mm重建间隔）获得仰卧位和俯卧位图像。由四位经验丰富的腹部放射科医生使用二维多平面重组，然后选择性使用三维内窥镜体绘制图像独立分析图像。每个息肉和每个patient.RESULTS：每个息肉的分析表明，合并的敏感性为0.68病变10毫米或更大（n= 40），与75%的四个读者之间的协议。每例患者的分析表明，检测和一致性得到改善，息肉或癌症10 mm或更大的患者（n= 28）的合并灵敏度为0.88，一致性为94%。当根据息肉大小阈值分析灵敏度和受试者操作特征分析时，读片者的结果在息肉直径约10 mm时收敛并达到峰值。结论：在该患者队列中，单探测器行CT结肠成像的诊断性能和观察者间一致性足以检测病变≥ 10 mm的患者，较小息肉的结果更具可变性。© RSNA，2002
PURPOSE:To prospectively evaluate multiobserver diagnostic performance and reader agreement for colorectal polyp detection in a well-characterized cohort of patients with increased number of polyps, compared with an average-risk patient, with colonoscopy as the reference standard.MATERIALS AND METHODS:A cohort of 70 patients suspected of having polyps was examined with spiral computed tomographic (CT) colonography, with colonoscopy performed the same day. After air insufflation per rectum, supine and prone images were obtained with single–detector row CT (5-mm collimation, 8-mm table increment, 2-mm reconstruction interval). Images were analyzed independently by four experienced abdominal radiologists using two-dimensional multiplanar reformation followed by selective use of three-dimensional endoscopic volume-rendered images. Data were analyzed both per polyp and per patient.RESULTS:Analysis per polyp demonstrated a pooled sensitivity of 0.68 for lesions 10 mm or larger (n= 40), with 75% agreement among the four readers. Analysis per patient demonstrated improved detection and agreement, with a pooled sensitivity of 0.88 for patients with polyps or cancers 10 mm or larger (n= 28), with 94% agreement. When sensitivity and receiver operating characteristic analyses were analyzed per polyp size threshold, results among readers converged and peaked at polyp diameters of approximately 10 mm.CONCLUSION:In this patient cohort, diagnostic performance and interobserver agreement with single–detector row CT colonography was sufficient for detection of patients with lesions 10 mm or larger, with more variable results for smaller polyps.© RSNA, 2002