A high-speed, high-performance, microfabricated comprehensive two-dimensional gas chromatograph
A high-speed, high-performance, microfabricated comprehensive two-dimensional gas chromatograph
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DOI：
10.1039/c9lc00027e
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发表时间：
2019-05-07
期刊：
影响因子：
6.1
通讯作者：
Simonson, Robert J.
中科院分区：
文献类型：
--
作者：
Whiting, Joshua J.;Myers, Edward;Simonson, Robert J.
一个小的，无消耗，低功耗，超高速的综合GCxGC系统，包括微加工柱，纳米机电系统（NEMS）悬臂梁谐振器的检测，和基于阀门的停流调制器的演示。使用Staiger阀歧管在一对微型柱上分离沸点范围为46至253 ° C的高极性29组分混合物，分离时间不到7秒，并且在整体滞留时间后仅超过4秒，用下游FID进行了证明。第二维的分析时间为160 ms，第二维的峰宽范围为10-60 ms。对于刚超过6 s的分离，计算出刚超过300的峰容量。数据从连续运行测试超过40天和20000运行的GCxGC柱与NEMS谐振器使用4个组件的测试集。GCxGC-NEMS谐振器系统生成的第二维峰宽窄至8 ms，由于检测器的欠采样而没有可辨别的峰失真。
A small, consumable-free, low-power, ultra-high-speed comprehensive GCxGC system consisting of microfabricated columns, nanoelectromechanical system (NEMS) cantilever resonators for detection, and a valve-based stop-flow modulator is demonstrated. The separation of a highly polar 29-component mixture covering a boiling point range of 46 to 253 degrees C on a pair of microfabricated columns using a Staiger valve manifold in less than 7 seconds, and just over 4 seconds after the ensemble holdup time is demonstrated with a downstream FID. The analysis time of the second dimension was 160 ms, and peak widths in the second dimension range from 10-60 ms. A peak capacity of just over 300 was calculated for a separation of just over 6 s. Data from a continuous operation testing over 40 days and 20000 runs of the GCxGC columns with the NEMS resonators using a 4-component test set is presented. The GCxGC-NEMS resonator system generated second-dimension peak widths as narrow as 8 ms with no discernable peak distortion due to under-sampling from the detector.